Heart Failure Reviews

, Volume 23, Issue 3, pp 461–468 | Cite as

Clinical correlates and pharmacological management of Asian patients with concomitant diabetes mellitus and heart failure

  • Yvonne May Fen Chia
  • Tiew-Hwa Katherine Teng
  • Chanchal Chandramouli
  • Jonathan Yap
  • Michael MacDonald
  • Carolyn S. P. LamEmail author


Asia is the center of convergence of the twin epidemics of diabetes mellitus (DM) and heart failure (HF). The regional and ethnic diversity across Asia, along with a high prevalence of a young, lean diabetic phenotype, emphasizes the importance of targeted public health strategies that address the unique needs of Asian patients with DM and HF. This review discusses the epidemiology, clinical correlates, pharmacological management, and outcomes of Asian patients with concomitant DM and HF.


Diabetes mellitus Heart failure Asia Pharmacotherapy Outcomes 



The ASIAN-HF study is supported by grants from National Medical Research Council of Singapore, A*STAR Biomedical Research Council ATTRaCT program, Boston Scientific Investigator Sponsored Research Program, and Bayer. The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation.

Compliance with ethical standards

Conflict of interest

Dr. Lam has no relevant disclosure for the present work.

Unrelated to present work: Research support or grants from National Medical Research Council of Singapore, non-financial support from Boston Scientific, non-financial support from Bayer, non-financial support from Thermofisher, non-financial support from Vifor Pharma, other from Bayer, other from Novartis, other from Takeda, other from Merck, other from Astra Zeneca, other from Janssen Research & Development, other from LLC, other from Menarini, other from Boehringer Ingelheim, other from Abbott Diagnostics, from DC Devices, outside the submitted work; in addition, Dr. Lam has a patent PCT/SG2016/050217 pending.

Dr. Chia, Dr. Teng, Dr. Chandramouli, Dr. Yap, and Dr. MacDonald declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Yvonne May Fen Chia
    • 1
  • Tiew-Hwa Katherine Teng
    • 2
    • 3
  • Chanchal Chandramouli
    • 2
  • Jonathan Yap
    • 2
  • Michael MacDonald
    • 4
  • Carolyn S. P. Lam
    • 1
    • 2
    • 5
    Email author
  1. 1.Duke-NUS Medical SchoolSingaporeSingapore
  2. 2.National Heart Centre SingaporeSingaporeSingapore
  3. 3.School of Population and Global HealthUniversity of Western AustraliaCrawleyAustralia
  4. 4.Changi General HospitalSingaporeSingapore
  5. 5.Cardiovascular Research InstituteNational University Heart CentreSingaporeSingapore

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