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Glycoconjugate Journal

, Volume 33, Issue 2, pp 121–123 | Cite as

Disaccharide analysis of chondroitin and heparin from farmed Atlantic salmon

  • Ragnar FlengsrudEmail author
Short Communication

Abstract

The heparin disaccharides detected in farmed Atlantic salmon (Salmo salar) gills and intestines have, with one exception, been reported in porcine heparin. The relative amounts of disaccharides appear to be very different in the two species. Two chondroitin disaccharides with a proposed essential role in the zebrafish (Danio rerio) development and differentiation are detected in farmed Atlantic salmon. In addition, most of the chondroitin/dermatan sulfate and heparin disaccharides detected here have been reported in zebrafish, in support of the claims of the heparin presence in fish. The same chondroitin/dermatan disaccharides were detected in the bones of bony fishes. The rare disaccharide UA2S-GalNAc that was found in trace amounts in all 5 bony fishes was found in relative high amounts in gills and in significant amounts in intestines. The rare heparin disaccharide UA2S-GlcN was in relative highest amounts both in gills and intestines. In context with our previous reports, this communication suggests that glycosaminoglycans in farmed Atlantic salmon heparin need further studies in order to clarify structure and function.

Keywords

Atlantic salmon Chondroitin disaccharides Heparin disaccharides Heparin pentasaccharide 

Notes

Compliance with ethical standards

Conflict of interest

The author declares no conflict of interest.

Supplementary material

10719_2016_9652_MOESM1_ESM.pdf (464 kb)
ESM 1 (PDF 464 kb)
10719_2016_9652_MOESM2_ESM.pdf (351 kb)
ESM 2 (PDF 350 kb)

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Department of Chemistry, Biotechnology and Food ScienceNorwegian University of Life Sciences (NMBU)ÅsNorway

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