, Volume 147, Issue 5–6, pp 401–409 | Cite as

Rate of change for the thermal adapted inversions in Drosophila subobscura

  • Goran Zivanovic
  • Conxita Arenas
  • Francesc MestresEmail author
Short Communication


The changes of chromosomal inversion polymorphism composition of Drosophila subobscura in samples from Apatin (Serbia) were studied in a 24-years interval (1994–2018). The variation was significant for all autosomes and directional, increasing the inversions considered as ‘warm’, whereas those reported as ‘cold’ decreased. Furthermore, the Chromosomal Thermal Index (CTI), which allows studying the thermal adaptation of the whole karyotype increased significantly in that period of time. These results were in agreement with the indicators of global warming in Apatin: a trend to increase of the mean, maximum and minimum (this latter even significant) temperatures, and an erratic pattern of rainfall (also usual in global warming). The deviations from the Wright–Fisher model of genetic drift were used to consider the possible effect of migration or selection as evolutionary factors responsible for the change in inversion frequencies. To quantify approximately the rate of change in the frequencies, for each kind of inversions (‘cold’, ‘warm’ and ‘non-thermal adapted’), the difference in frequency between the Apatin samples obtained in 1994 and 2018 was computed and then it was divided by the number of years elapsed. This rate was always higher (from twice as many as thirty times more depending on the autosome) for thermal adapted inversions (‘cold’ or ‘warm’) than the ‘non-thermal’ adapted. From this study, it could be concluded that the chromosomal inversions of D. subobscura could change (in composition and frequencies) in a predictable direction and a rather ‘rapid’ rhythm to adapt to the global warming scenario.


Chromosomal inversions Adaptation Selection Temperature Global warming Evolutionary rate 



We want to dedicate this research to Prof. A. Prevosti on the occasion of the centenary of his birth (1919–2019). We especially thank the comments and suggestions of the anonymous reviewers who clearly improved the earlier version of the manuscript. This research was financially supported by grants from the Ministry of Education, Science and Technological Development of the Republic of Serbia (Grant Number 173025), the Ministerio de Economía y Competitividad, Spain (CTM2017-88080 AEI/FEDER, UE) and the Generalitat de Catalunya, Spain (2017SGR 1120 and 2017SGR 622).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

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Supplementary material 1 (DOCX 166 kb)
10709_2019_78_MOESM2_ESM.docx (16 kb)
Supplementary material 2 (DOCX 15 kb)


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Genetics, Institute for Biological Research “Sinisa Stankovic”University of BelgradeBelgradeSerbia
  2. 2.Departament de Genètica, Microbiologia i Estadística, Secció EstadísticaUniversitat de BarcelonaBarcelonaSpain
  3. 3.Departament de Genètica, Microbiologia i Estadística, Secció Genètica Biomèdica, Evolució i Desenvolupament, Facultat de BiologiaUniversitat de BarcelonaBarcelonaSpain
  4. 4.IRBio – Institut de Recerca de la BiodiversitatUniversitat de BarcelonaBarcelonaSpain

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