Genetica

, Volume 125, Issue 2–3, pp 333–339 | Cite as

The Fundamental Theorem of Neutral Evolution: Rates of Substitution and Mutation Should Factor in Premeiotic Clusters

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Abstract

Mutations do not always arise as single events. Many new mutations actually occur in the cell lineage before germ cell formation or meiosis and are therefore replicated premeiotically. The increased likelihood of substitutions caused by these clusters of new mutant alleles can change the fundamental theorem of neutral evolution.

Keywords

clusters mutations neutral alleles premeiotic mutants substitutions 
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Copyright information

© Springer 2005

Authors and Affiliations

  1. 1.Department of Biological SciencesBowling Green State UniversityBowling GreenUSA
  2. 2.Department of ZoologyUniversity of OklahomaNormanUSA

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