Study of Complexes of Polymethacrylate Guanidine with Magnesium Ions
- 29 Downloads
New polymer compounds of methacrylate guanidine with magnesium ions were synthesized and studied. IR spectroscopy and x-ray phase analysis were used to show that polymethacrylate guanidine and magnesium ions strongly interact with each other to form a new coordination compound. The metal-containing complexes are formed through intermolecular coordination of the metal ions with the oxygen atom of the carboxylate ion and nitrogen atom of the amino group of the guanidine fragment on the polymer surface. The antimicrobial activity of these metal complexes was studied relative to gram positive and gram negative test strains. The introduction of metal ions into polymethacrylate guanidine enhances the antimicrobial activity of these materials and expands the spectrum of their bactericidal action.
- 1.A. V. Alesenko, E. B. Burlakova, and E. A. Pantaz, Biokhimiya, 49, No. 4, 621-628 (1984).Google Scholar
- 4.A. N. Tentsova and M. T. Alyushin (editors), Polymers in Pharmacology [in Russian], Meditsina, Moscow (1985).Google Scholar
- 5.T. A. Baitykalov, T. A. Lobaeva, et al., Vestnik Ross. Univ. Druzhby Narodov, Ser. Meditsina, 25, No. 1, 20-26 (2004).Google Scholar