Familial Cancer

, Volume 12, Issue 3, pp 573–576 | Cite as

A case of pneumatosis cystoides intestinalis mimicking familial adenomatous polyposis

  • Maurizio Ponz de Leon
  • Claudia Bertarelli
  • Gian Piero Casadei
  • Andrea Grilli
  • Patrizia Bacchini
  • Monica Pedroni
  • Elio Jovine
Short Communication

Abstract

In rare cases the diagnosis of Familial Adenomatous Polyposis (FAP) may not be simple or straightforward. We describe the case of a 54-year man in whom endoscopic and histological features of FAP led to proctocolectomy with ileoanal anastomosis. At anatomical examination, air-filled cystic formations in the submucosa and subserosa of the entire large bowel led to the diagnosis of “Pneumatosis Cystoides Intestinalis”, a rare clinical condition featured by the infiltration (or the production) of gas within the intestinal wall. In this case the disease was associated with a long-lasting ingestion of acarbose; as suggested by previous reports, it is possible that gas produced by the fermentation of this unabsorbable carbohydrate penetrates the bowel wall giving origin to cystic formation and to the endoscopic appearance of several polypoid lesions in the large bowel. This report indicates that in rare occasions Pneumatosis Intestinalis can lead to a wrong diagnosis of FAP.

Keywords

Colon Rectum Polyp Pneumatosis Cystoides Tumor 

Notes

Conflicts of interest

No conflict of interest involves the Authors of the present investigation.

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Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  • Maurizio Ponz de Leon
    • 1
    • 5
  • Claudia Bertarelli
    • 2
  • Gian Piero Casadei
    • 2
  • Andrea Grilli
    • 3
  • Patrizia Bacchini
    • 3
  • Monica Pedroni
    • 1
  • Elio Jovine
    • 4
  1. 1.Dipartimento di Medicina InternaUniversità di Modena e Reggio EmiliaModenaItaly
  2. 2.Anatomia PatologicaOspedale MaggioreBolognaItaly
  3. 3.Endoscopia Digestiva e Anatomia PatologicaCasa di Cura Villa ErbosaBolognaItaly
  4. 4.Dipartimento Chirurgico, Chirurgia AOspedale MaggioreBolognaItaly
  5. 5.Dipartimento di Medicina DiagnosticaClinica e di Sanità Pubblica, PoliclinicoModenaItaly

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