Familial Cancer

, Volume 10, Issue 3, pp 501–503

Familial breast cancer: is it time to move from a reactive to a proactive role?

  • H. Harris
  • I. Nippert
  • C. Julian-Reynier
  • J. Schmidtke
  • C. van Asperen
  • D. Gadzicki
  • A. Tibben
  • D. G. Evans
Article

DOI: 10.1007/s10689-011-9434-1

Cite this article as:
Harris, H., Nippert, I., Julian-Reynier, C. et al. Familial Cancer (2011) 10: 501. doi:10.1007/s10689-011-9434-1

Abstract

In 2004 the NICE guidelines on familial breast cancer advised Health Care Professionals that they should not actively seek to identify women with a family history of breast cancer. We have carried out a review of the evidence base and a large scale questionnaire survey of health professionals in four European countries. There is overwhelming support amongst GPs and surgeons against the premise that that health care professionals should not be proactive in identifying patients at risk of familial breast cancer. This that suggest the time is right to overturn the NICE decision.

Keywords

BRCA1 BRCA2 Breast cancer Screening Mortality Proactive 

Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • H. Harris
    • 3
  • I. Nippert
    • 5
  • C. Julian-Reynier
    • 4
  • J. Schmidtke
    • 6
  • C. van Asperen
    • 9
  • D. Gadzicki
    • 10
  • A. Tibben
    • 7
    • 8
  • D. G. Evans
    • 1
    • 2
  1. 1.Genetic Medicine MAHSCCentral Manchester University Hospitals NHS Foundation TrustManchesterUK
  2. 2.Genesis Prevention CentreUniversity Hospital South ManchesterManchesterUK
  3. 3.GenEd Coordinating CentreUniversity of ManchesterManchesterUK
  4. 4.U912, INSERM, IRDAix-Marseille Université, Institut Paoli- CalmettesMarseilleFrance
  5. 5.Women’s Health ResearchWestfaelische Wilhelms-Universitaet, Münster Medical SchoolMünsterGermany
  6. 6.Institute of Human GeneticsHannover Medical SchoolHannoverGermany
  7. 7.Centre of Human and Clinical GeneticsLeiden University Medical Centre (LUMC)LeidenThe Netherlands
  8. 8.Department of Clinical GeneticsErasmus MCRotterdamThe Netherlands
  9. 9.Department of Clinical Genetics, Centre for Human and Clinical GeneticsLeiden University Medical Centre (LUMC)LeidenThe Netherlands
  10. 10.Institute of Cell and Molecular PathologyHannover Medical SchoolHannoverGermany

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