Journal of Engineering Mathematics

, Volume 63, Issue 1, pp 121–133

Numerical approximation of bioluminescence tomography based on a new formulation



Bioluminescence tomography (BLT) is a promising new method in biomedical imaging. The BLT problem is an ill-posed inverse source problem, usually studied through a regularization technique. A new approach is proposed for solving the BLT problem based on an adjoint equation. Numerical examples show that the new formulation allows us to obtain accurate solutions.


Bioluminescence tomography Finite-element methods Inverse problem 


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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  1. 1.Department of MathematicsZhejiang UniversityHangzhouPeople’s Republic of China
  2. 2.Department of MathematicsUniversity of IowaIowa CityUSA

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