Journal of Engineering Mathematics

, Volume 63, Issue 1, pp 121–133

Numerical approximation of bioluminescence tomography based on a new formulation

Article

Abstract

Bioluminescence tomography (BLT) is a promising new method in biomedical imaging. The BLT problem is an ill-posed inverse source problem, usually studied through a regularization technique. A new approach is proposed for solving the BLT problem based on an adjoint equation. Numerical examples show that the new formulation allows us to obtain accurate solutions.

Keywords

Bioluminescence tomography Finite-element methods Inverse problem 

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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  1. 1.Department of MathematicsZhejiang UniversityHangzhouPeople’s Republic of China
  2. 2.Department of MathematicsUniversity of IowaIowa CityUSA

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