The characteristics of indoor and outdoor fungi and their relation with allergic respiratory diseases in the southern region of Turkey

  • Tugba Arikoglu
  • Sehra Birgul Batmaz
  • Taner Coşkun
  • Feza Otag
  • Didem Derici Yildirim
  • Semanur Kuyucu
Article

Abstract

Indoor and outdoor fungal exposure has been shown to be associated with the development of allergic respiratory diseases. The aim of the study was to investigate the types and concentrations of airborne fungi inside and outside homes and evaluate the association between fungal levels and allergic diseases in the southern region of Turkey. A total of 61 children admitted with respiratory complaints to the pediatric allergy clinic between September 2007 and November 2008 were included in this study. The air samples were obtained using the Air IDEAL volumetric air sampler longitudinally for 1 year. A comprehensive questionnaire was used for medical history and housing conditions. Skin prick test was performed to determine fungal sensitivity and spirometric indices were employed. The predominant indoor fungal species were Cladosporium (69.3 %), Penicillium (18.9 %), Aspergillus (6.5 %), and Alternaria (3.1 %). A strong correlation between indoor and outdoor fungal levels was detected for the Cladosporium species (p < 0.001, r = 0.72) throughout the year. Living in a detached home (p = 0.036) and the presence of cockroaches (p = 0.005) were associated with total indoor fungal levels. The presence of cockroaches (aOR 3.5; 95 % CI 0.95–13.10, p = 0.059) was also associated with fungal sensitization at the edge of significance. The statistical cutoff values of indoor and outdoor Cladosporium levels to predict symptomatic asthma were found to be >176 CFU/m3 (p = 0.003, AUC 0.696; sensitivity 65.5 %; specificity 68.7 %) and >327 CFU/m3 (p = 0.038; AUC 0.713; sensitivity 66.6 %; specificity 76.9 %), respectively. Children with respiratory symptoms are exposed to a considerable level of fungi inside and outside their homes. The prevention of fungal exposure may provide valuable intervention for respiratory diseases.

Keywords

Indoor fungi Outdoor fungi Air sampling Allergic diseases Fungal sensitivity House characteristics 

Notes

Acknowledgments

No special funding was received.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Tugba Arikoglu
    • 1
  • Sehra Birgul Batmaz
    • 1
  • Taner Coşkun
    • 2
  • Feza Otag
    • 2
  • Didem Derici Yildirim
    • 3
  • Semanur Kuyucu
    • 1
  1. 1.Department of Pediatric Allergy Immunology, Faculty of MedicineMersin UniversityMersinTurkey
  2. 2.Department of Microbiology, Faculty of MedicineMersin UniversityMersinTurkey
  3. 3.Faculty of Medicine, Department of BiostatisticsMersin UniversityMersinTurkey

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