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European Journal of Epidemiology

, Volume 28, Issue 5, pp 383–392 | Cite as

Consumption of alcohol and risk of cancer among men: a 30 year cohort study in Lithuania

  • Ruta EverattEmail author
  • Abdonas Tamosiunas
  • Dalia Virviciute
  • Irena Kuzmickiene
  • Regina Reklaitiene
CANCER

Abstract

Studies have indicated hazardous consumption of large quantities of alcohol among adults in Lithuania. We assessed the associations of alcohol consumption at baseline with cancer incidence among men in a population-based cohort study, using Cox models adjusted for smoking, education and body mass index. Attained age was used as a time-scale. During follow-up (1978–2008) 1,698 men developed cancer. A higher amount of alcohol consumption (≥140.1 g/week vs. 0.1–10.0 g/week) was positively associated with increased risk of total cancer [hazard ratio (HR) = 1.36, 95 % confidence interval (95 % CI) 1.11, 1.65], upper aerodigestive tract cancer (HR = 2.79, 95 % CI 1.23, 6.34) and alcohol-related cancers (i.e. oral cavity, pharynx, larynx, oesophagus, colorectal and liver cancer) (HR = 1.88, 95 % CI 1.25, 2.85). Compared to occasional drinkers (a few times/year), drinkers 2–7 times/week showed an increased risk of total (HR = 1.45, 95 % CI 1.16, 1.83), alcohol-related (HR = 1.83 95 % CI 1.14, 2.93) and other cancers (HR = 1.35, 95 % CI 1.04, 1.76). Our results showed no statistically significant associations between quantity of alcohol intake per one occasion and risk of cancer. About 13 % of total, 35 % of upper aerodigestive tract, 22 % of alcohol-related and 10 % of other cancer cases were due to alcohol consumption in this cohort of men.

Keywords

Cancer Alcohol consumption Cohort studies 

Notes

Acknowledgments

This research was funded by a Grant (No. LIG-07/2010) from the Research Council of Lithuania. We wish to thank the staff of the Lithuanian Cancer Registry and Lithuanian Residents’ Register Service for making data available.

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Ruta Everatt
    • 1
    Email author
  • Abdonas Tamosiunas
    • 2
  • Dalia Virviciute
    • 2
  • Irena Kuzmickiene
    • 1
  • Regina Reklaitiene
    • 2
  1. 1.Group of Epidemiology, Institute of OncologyVilnius UniversityVilniusLithuania
  2. 2.Laboratory of Population Studies, Institute of Cardiology, Medical AcademyLithuanian University of Health SciencesKaunasLithuania

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