European Journal of Epidemiology

, Volume 25, Issue 12, pp 885–893 | Cite as

The Shanghai Changfeng Study: a community-based prospective cohort study of chronic diseases among middle-aged and elderly: objectives and design

  • Xin Gao
  • Albert Hofman
  • Yu Hu
  • Huandong Lin
  • Chouwen Zhu
  • Johannes Jeekel
  • Xuejuan Jin
  • Jiyao Wang
  • Jian Gao
  • Yiqing Yin
  • Naiqing Zhao
New Study


The Shanghai Changfeng Study is a community-based prospective cohort study of chronic diseases ongoing since February 2009 in Shanghai, China. The study focuses on multiple chronic diseases, including obesity and metabolic syndrome, diabetes, osteoporosis, liver diseases, cardiovascular diseases and neurologic diseases. 15,000 subjects of 40 years or over are planned to be recruited. The rationale, objectives and design of this study are described in this paper.


Cohort study Obesity Metabolic syndrome Diabetes Cardiovascular disease Liver diseases Osteoporosis Genetic and biomarker studies 



The Shanghai Changfeng Study has received the funding from: (1) Asia Facility for China (Grant No. AF 06/CH/22); (2) National Key Technologies R&D Program (Grant No. 2008 BAI52B03); and (3) Major Project of Subject Construction of Shanghai Bureau of Health (Grant No.08GWZX0203). The Shanghai Changfeng Study has also received great support from Changfeng Health Center, the Health Bureau of Putuo District, and the committees of all the sub-communities of Changfeng. The contributions of all the working staffs and inhabitants are greatly acknowledged.


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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Xin Gao
    • 1
  • Albert Hofman
    • 2
  • Yu Hu
    • 3
  • Huandong Lin
    • 1
  • Chouwen Zhu
    • 4
    • 7
  • Johannes Jeekel
    • 5
  • Xuejuan Jin
    • 6
  • Jiyao Wang
    • 7
  • Jian Gao
    • 8
  • Yiqing Yin
    • 9
  • Naiqing Zhao
    • 10
  1. 1.Department of Endocrinology and Metabolism, Zhong Shan HospitalFudan UniversityShanghaiChina
  2. 2.Department of EpidemiologyErasmus Medical CenterRotterdamThe Netherlands
  3. 3.Department of Geriatrics, Clinical Epidemiology Center, Zhong Shan HospitalFudan UniversityShanghaiChina
  4. 4.Department of Foreign AffairsFudan UniversityShanghaiChina
  5. 5.Department of NeuroscienceErasmus Medical CenterRotterdamThe Netherlands
  6. 6.Clinical Epidemiology Center, Zhong Shan HospitalFudan UniversityShanghaiChina
  7. 7.Department of Gastroenterology, Clinical Epidemiology Center, Zhong Shan HospitalFudan UniversityShanghaiChina
  8. 8.Department of Clinical Nutrition, Zhong Shan HospitalFudan UniversityShanghaiChina
  9. 9.Computer and Network Center, Zhong Shan HospitalFudan UniversityShanghaiChina
  10. 10.Department of Biostatistics, College of Public HealthFudan UniversityShanghaiChina

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