European Journal of Epidemiology

, Volume 21, Issue 3, pp 245–247 | Cite as

Nitrate in Community Water Supplies and Risk of Childhood Type 1 Diabetes in Sardinia, Italy

  • Sandro Muntoni
  • Pierluigi CoccoEmail author
  • Sergio Muntoni
  • Gabriella Aru
Letters to the Editor


We tested the hypothesis of an association between childhood type 1 diabetes (T1D) risk and nitrate concentration in drinking water in Sardinia, Italy, using Poisson regression analysis. Childhood T1D risk showed an inverse trend with increasing quartile of nitrate level in the total population and among men. A nitrate concentration in drinking water below 10 mg/l is unlikely to account for the spatial variation in childhood T1D incidence.


Childhood type 1 diabetes Drinking water Ecology Environmental epidemiology Nitrate 


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Copyright information

© Springer 2006

Authors and Affiliations

  • Sandro Muntoni
    • 1
    • 2
  • Pierluigi Cocco
    • 3
    Email author
  • Sergio Muntoni
    • 2
  • Gabriella Aru
    • 3
  1. 1.Department of Toxicology, Oncology and Molecular Pathology UnitUniversity of CagliariCagliariItaly
  2. 2.Center for Metabolic Diseases and AtherosclerosisThe ME.DI.CO. AssociationCagliariItaly
  3. 3.Department of Public Health, Occupational Health SectionUniversity of CagliariCagliariItaly

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