European Journal of Epidemiology

, Volume 20, Issue 11, pp 925–927

Epidemiological Survey of Tourette Syndrome in Children and Adolescents in Wenzhou of P.R. China

  • Rong Jin
  • Rong-yuan Zheng
  • Wen-wu Huang
  • Hui-qin Xu
  • Bei Shao
  • Hong Chen
  • Liang Feng
Neurological Diseases

Abstract

An epidemiological survey on Tourette syndrome (TS) in a developing country is relatively scarce. This study was conducted to investigate the prevalence and distribution of TS in children and juveniles aged 7–16 years in Wenzhou of P.R. China. A total of 9742 children and adolescents were included in this survey. Cross-sectional study with stratified-cluster sampling method was used. The prevalence of TS among school-age children was estimated to be an average of 0.43%. The ratio of␣male to female was 10.6 to 1 (0.74% for males and 0.07% for females). Pupils in the age range of 7–16 years are more likely to have comorbid disorders. The mean age at onset of TS was 7.7±2.7 years, with 45.2% of them at the age of 6–7. The rate of delayed diagnosis, misdiagnosis and misclassification of the syndrome were 78.6, 42.9 and 23.8%, respectively. This survey supports that TS is a common disease prevalent amongst children and juveniles in Wenzhou area of P.R. China, and its incidence was correlated with age and sex and often misdiagnosed and misclassified.

Keywords

Children and adolescents Epidemiology Tourette syndrome 

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References

  1. 1.
    Freeman, RD, Fast, DK, Burd, L, Kerbeshian, J, Robertson, MM, Sandor, P 2000An international perspective on Tourette syndrome: Selected findings from 3,500 individuals in 22 countriesDev Med Child Neurol42436447CrossRefPubMedGoogle Scholar
  2. 2.
    Apter, A, Pauls, DL, Bleich, A,  et al. 1993An epidemiologic study of Gilles de la Tourette’s syndrome in IsraelArch Gen Psychiatr50734738PubMedGoogle Scholar
  3. 3.
    Caine, ED, McBride, MC, Chiverton, P, Bamford, KA, Rediess, S, Shiao, J 1988Tourette’s syndrome in Monroe County school childrenNeurology38472475PubMedGoogle Scholar
  4. 4.
    Zheng, RY, Jin, R, Zhang Lei, , Shao, B, He, JC, Wang, XH 2002Observation of clinical effects and movement disorders features on 305 cases of Tourette syndromeChinese J Clin Rehabil615981599Google Scholar
  5. 5.
    Comings, DE, Himes, JA, Comings, BG 1990An epidemiologic study of Tourette’s syndrome in a single school districtJ Clin Psychiatr51463469Google Scholar
  6. 6.
    Tanner, CM, Goldman, SM 1997Epidemiology of Tourette syndromeNeurol Clin15395402CrossRefPubMedGoogle Scholar
  7. 7.
    Staley, D, Wand, R, Shady, G 1997Tourette disorder: A␣cross-cultural reviewCompr Psychiatr38616Google Scholar
  8. 8.
    Kurlan, R 1992The pathogenesis of Tourette’s syndrome. A possible role for hormonal and excitatory neurotransmitter influences in brain developmentArch Neurol49874876PubMedGoogle Scholar
  9. 9.
    Burd, L, Kerbeshian, J, Wikenheiser, M, Fisher, W 1986A Prevalence study of Gilles de la Tourette syndrome in North Dakota school-age childrenJ Am Acad Child Psychiatr25552553Google Scholar
  10. 10.
    Burd, L, Kerbeshian, J, Wikenheiser, M, Fisher, W 1986Prevalence of Gilles de la Tourette’s syndrome in North Dakota adultsAm J Psychiatr143787788PubMedGoogle Scholar
  11. 11.
    Liu, ZS 1998Questions and answers about Tourette syndromeJ Appl Clin Pediatr13347349Google Scholar
  12. 12.
    Wand, R, Shady, G, Broder, R, Furer, P, Staley, D 1992Tourette syndrome: Issues in diagnosisNeurosci Biobehav Rev16449451PubMedGoogle Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • Rong Jin
    • 1
  • Rong-yuan Zheng
    • 2
  • Wen-wu Huang
    • 3
  • Hui-qin Xu
    • 2
  • Bei Shao
    • 2
  • Hong Chen
    • 4
  • Liang Feng
    • 1
  1. 1.Department of EpidemiologyThe First Affiliated Hospital of Wenzhou Medical CollegeWenzhouP.R. China
  2. 2.Department of NeurologyThe First Affiliated Hospital of Wenzhou Medical CollegeWenzhouP.R. China
  3. 3.The Psychiatric Hospital of WenzhouWenzhouP.R. China
  4. 4.Department of PsychiatryThe First Affiliated Hospital of Wenzhou Medical CollegeWenzhouP.R. China
  5. 5.Department of EpidemiologyThe First Affiliated Hospital of Wenzhou Medical CollegeWenzhouChina

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