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Non-invasive assessment of coronary calcification

  • Rozemarijn VliegenthartEmail author
  • Hok-Hay S. Oei
  • Albert Hofman
  • Matthijs Oudkerk
  • Jackqueline C. M. Witteman
Review

Abstract

Electron-beam tomography (EBT) and multi-detector computed tomography (MDCT) enable the noninvasive assessment of coronary calcification. The amount of coronary calcification, as detected by EBT, has a close relation with the amount of coronary atherosclerosis, which is the substrate for the occurrence of myocardial infarction and sudden cardiac death. Calcification of the coronary arteries can be seen as a cumulative measure of life-time exposure to cardiovascular risk factors. Several studies have shown that the amount of coronary calcification is associated with the risk of coronary heart disease. Therefore, coronary calcification is a promising method for non-invasive detection of asymptomatic subjects at high risk of developing coronary heart disease. Whether measurement of coronary calcification also increases the predictive power of coronary events based on cardiovascular risk factors is topic of current research.

Keywords

Atherosclerosis Epidemiology Imaging Myocardial infarction Population 

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Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Rozemarijn Vliegenthart
    • 1
    Email author
  • Hok-Hay S. Oei
    • 1
  • Albert Hofman
    • 1
  • Matthijs Oudkerk
    • 1
  • Jackqueline C. M. Witteman
    • 1
  1. 1.Department of RadiologyUniversity Hospital GroningenGroningenThe Netherlands

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