European Journal of Epidemiology

, Volume 20, Issue 2, pp 183–199

Exposure to ambient air pollution and prenatal and early childhood health effects

  • Marina Lacasaña
  • Ana Esplugues
  • Ferran Ballester
Developmental Epidemiology

Abstract

Over the last years, concern for the possible influence of exposure to air pollutants in children during gestation or the first years of life has grown; exposure levels which may be reached nowadays in our dwellings and in our streets. In the present study evidence over the possible impact of ambient air pollution on the foetus and the infants (i.e.: less than 1 year) published during the last decade, 1994–2003, are revised. Studies on infant mortality and exposure to particles show an outstanding consistence in the magnitude of the effects, despite the different designs used. As a whole, data show that an increase in 10 μg/m3of particle concentration (measured as PM10) is associated with to about 5% increase in post-neonatal mortality for all causes and around 22% for post-neonatal mortality for respiratory diseases. Regarding damage in foetal health, although results are not always consistent, most studies show associations with exposure to air pollution during pregnancy. However, the precise mechanisms of action of air pollutants on adverse reproductive results are still unknown, so is the period of exposure most relevant during pregnancy and the specific pollutant which may represent a higher risk. Follow-up studies evaluating personal exposure to different air pollutants are required, allowing for the adequate evaluation of the impact of each pollutant in different periods of pregnancy, as well as providing hypotheses on their possible mechanisms of action.

Keywords

Ambient air pollution Congenital defects Intrauterine growth retardation Low birth weight Mortality Preterm delivery 

Abbreviations

BW

birth weight

CI

confidence interval

CO

carbon monoxide

IQR

interquartile range

IUGR

intrauterine growth retardation

LBW

low birth weight

NOx

nitrogen oxides

O3

ozone

PAH

polycyclic aromatic hydrocarbons

PCB

polichlorinated biphenyls

PM10

particles ≤ 10 μm diameter

PM2.5

particles ≤ 2.5 μm diameter

TSP

total suspended particles

SGA

small for gestational age

SIDS

sudden infant death syndrome

SMR

standardized mortality ratio

SO2

sulphur dioxide

WP

weeks of pregnancy

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Copyright information

© Springer 2005

Authors and Affiliations

  • Marina Lacasaña
    • 1
    • 2
    • 3
  • Ana Esplugues
    • 1
    • 2
  • Ferran Ballester
    • 1
    • 4
  1. 1.Epidemiology and Statistics UnitValencian School of Studies for HealthValenciaSpain
  2. 2.University Hospital La FeValenciaSpain
  3. 3.Center for Environmental Health, Center for Research in Populational HealthNational Institute of Public HealthCuernavacaMexico
  4. 4.Public Health Department, History of Science and GynaecologyMiguel Hernández UniversityAlicanteSpain

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