Investigational New Drugs

, Volume 28, Issue 2, pp 199–202 | Cite as

Hemangiopericytoma and antiangiogenic therapy: clinical benefit of antiangiogenic therapy (sorafenib and sunitinib) in relapsed Malignant Haemangioperyctoma /Solitary Fibrous Tumour

  • Julien Domont
  • Christophe Massard
  • Nathalie Lassau
  • Jean-Pierre Armand
  • Axel Le Cesne
  • Jean-Charles Soria
SHORT REPORT

Keywords

Sarcoma Antiangiogenic Sorafenib Sunitinib Functional imaging 

Notes

Acknowledgement

The authors thank Lorna Saint Ange for editing.

References

  1. 1.
    Gengler C, Guillou L (2006) Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology 48(1):63–74. doi: 10.1111/j.1365-2559.2005.02290.x ReviewCrossRefPubMedGoogle Scholar
  2. 2.
    Park MS, Patel SR, Ludwig JA, Trent JC, Conrad CA, Lazar AJ, Choi H, Benjamin RS, Araujo DM (2008) Combination therapy with temozolomide and bevacizumab in the treatment of hemangiopericytoma/malignant solitary fibrous tumor. J Clin Oncol 26:(May 20 suppl; abstr 10512)Google Scholar
  3. 3.
    Faivre S, Delbaldo C, Vera K, Robert C, Lozahic S, Lassau N, Bello C, Deprimo S, Brega N, Massimini G, Armand JP, Scigalla P, Raymond E (2006) Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 24(1):25–35. doi: 10.1200/JCO.2005.02.2194 CrossRefPubMedGoogle Scholar
  4. 4.
    DuBois S, Demetri G (2007) Markers of angiogenesis and clinical features in patients with sarcoma. Cancer 109(5):813–819. doi: 10.1002/cncr.22455 ReviewCrossRefPubMedGoogle Scholar
  5. 5.
    Balasubramanian L, Evens AM (2006) Targeting angiogenesis for the treatment of sarcoma. Curr Opin Oncol 18(4):354–359. doi: 10.1097/01.cco.0000228741.64541.ca ReviewCrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Julien Domont
    • 1
  • Christophe Massard
    • 2
  • Nathalie Lassau
    • 3
  • Jean-Pierre Armand
    • 2
  • Axel Le Cesne
    • 1
  • Jean-Charles Soria
    • 2
  1. 1.Department of Medicine, Sarcoma GroupInstitut Gustave RoussyVillejuifFrance
  2. 2.Université Paris XI, SITEP (Service des Innovations Thérapeutiques Précoces), Département de MédecineInstitut Gustave RoussyVillejuifFrance
  3. 3.Imaging DepartmentInstitut Gustave RoussyVillejuifFrance

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