Documenta Ophthalmologica

, Volume 121, Issue 1, pp 51–62 | Cite as

The electroretinogram: a useful tool for evaluating age-related macular disease?

  • Emma J. BerrowEmail author
  • Hannah E. Bartlett
  • Frank Eperjesi
  • Jonathan M. Gibson


With an ageing population, the number of age-related macular disease (ARMD) cases will inevitably rise. This gives greater impetus for the need to identify the disease earlier and assess treatments to slow disease progression. Differing electroretinogram (ERG) modalities have been reviewed in relation to the objective assessment of retinal function in ARMD and for monitoring the effectiveness of clinical interventions. Conflicting results have been found with regard to the efficacy of ERG findings in the investigation of ARMD in previous years. The newer multifocal ERG paradigm provides spatial topographical information about retinal function in ARMD. It has shown promising results in monitoring effectiveness of clinical interventions and studies are continuing in this area. Better knowledge of retinal function in ARMD may lead to enhanced treatments at each phase of the disease.


Electroretinography Maculopathy Age-related macular degeneration Multifocal electroretinogram 



The authors thank Dr Mohammad Laiquzzaman for helpful editorial comments.

Competing Interests



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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Emma J. Berrow
    • 1
    • 2
    Email author
  • Hannah E. Bartlett
    • 1
  • Frank Eperjesi
    • 1
  • Jonathan M. Gibson
    • 1
    • 2
  1. 1.Ophthalmic Research Group, School of Life and Health SciencesAston UniversityBirminghamUnited Kingdom
  2. 2.Heart of England NHS TrustBirminghamUnited Kingdom

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