Fragility of Life: Recurrent Intestinal Perforation Due to Vascular Ehlers–Danlos Syndrome

  • Lindsay A. SceatsEmail author
  • Preeti A. Sukerkar
  • Shyam S. Raghavan
  • Alaleh Esmaeili Shandiz
  • Andrew Shelton
  • Cindy Kin
Stanford Multidisciplinary Seminars

Case Presentation and Evolution

A 29-year-old woman was evaluated in the emergency department for fevers and lower abdominal pain. She had recently been admitted to an outside hospital for diverticulitis and treated with intravenous antibiotics. Abdominal computed tomography (CT) was interpreted as showing complicated sigmoid diverticulitis with associated abscess. Past medical history was notable for two prior episodes of complicated diverticulitis; one episode involved colonic perforation while the patient was 3 months pregnant that resulted in pregnancy loss. This was managed with a Hartmann’s procedure that was later reversed. She had previously undergone cholecystectomy and two cesarean sections without complications.

She was initially treated with intravenous antibiotics, bowel rest, and percutaneous abscess drainage. Given her young age and history of repeated abdominal abscesses and perforation, there was clinical concern for Crohn’s disease. She underwent magnetic resonance...


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Lindsay A. Sceats
    • 1
    Email author
  • Preeti A. Sukerkar
    • 2
  • Shyam S. Raghavan
    • 3
  • Alaleh Esmaeili Shandiz
    • 3
  • Andrew Shelton
    • 1
  • Cindy Kin
    • 1
  1. 1.Division of Colorectal Surgery, Department of General SurgeryStanford University School of MedicineStanfordUSA
  2. 2.Department of RadiologyStanford University School of MedicineStanfordUSA
  3. 3.Department of PathologyStanford University School of MedicineStanfordUSA

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