Repetitive Position Change Improves Gastric Cleanliness for Magnetically Controlled Capsule Gastroscopy
Background and Aims
Good gastric preparation is essential for magnetically controlled capsule gastroscopy (MCCG) examination. This study aims to determine if repetitive position change after dimethicone premedication could further improve gastric cleanliness for MCCG.
Consecutive patients referred for MCCG in our center from May 7 to May 31, 2018 were prospectively enrolled and randomized to undergo repetitive position change for 15 min (position change group) or not (conventional group) after ingesting dimethicone. Primary outcome was gastric cleanliness score and secondary outcomes were detection rate of positive findings, number of lesions per patient, gastric examination time, and safety of MCCG.
Totals of 43 and 40 were included in the position change and conventional groups, respectively. Gastric cleanliness score in the position change group was significantly higher than in the conventional group (21.2 ± 1.0 vs. 18.6 ± 2.0, P < 0.001), as was the proportion of acceptable gastric cleanliness (gastric cleanliness score ≥ 18) (100% vs. 72.5%, P < 0.001). There was no statistical difference in detection rate of positive findings between the two groups (27.9% vs. 27.5%, P = 0.97). In the position change group, the gastric examination time was significantly reduced (13.2 ± 4.0 vs. 15.3 ± 5.1, P = 0.043). No adverse events were observed.
Repetitive position change after dimethicone premedication significantly improves gastric cleanliness for MCCG examination.
Clinical Trial Registration ClinicalTrials.gov, ID: NCT03514966.
KeywordsPosition change Gastric cleanliness Dimethicone Magnetically controlled capsule gastroscopy
Study concept and design (ZL); registration of the study (YCW, JP); conduct of the study (YCW, JP); acquisition of data (YCW, XJS, XJ, WBZ, YYQ, WZ, XL, JY, XNY, AJZ); analysis and interpretation of data (YCW, JP); drafting of the manuscript (JP); statistical analysis (YCW); critical revision of the manuscript for important intellectual content (ZL, ZSL); obtained funding (ZL, JP). All authors had access to the study data and reviewed and approved the final manuscript.
This study is supported by grants from the National Natural Science Foundation of China (to Z. Liao, No. 81422010); Foundation for the Author of National Excellent Doctoral Dissertation of China (to Z. Liao, No. 201271); the Shuguang Program of Shanghai Education Development Foundation and Shanghai Municipal Education Commission (to Z. Liao, No. 15SG33); the Chang Jiang Scholars Program of Ministry of Education (to Z. Liao, No. Q2015190); and Shanghai Sailing Program (to J. Pan, No. 18YF1422800), China.
Conflicts of interest
The authors have no conflicts of interest or financial ties to disclose.
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