Digestive Diseases and Sciences

, Volume 63, Issue 5, pp 1148–1157 | Cite as

Impact on Health-Related Quality of Life in Adults with Eosinophilic Gastritis and Gastroenteritis: A Qualitative Assessment

  • Alyse BedellEmail author
  • Tiffany Taft
  • Meredith R. Craven
  • Livia Guadagnoli
  • Ikuo Hirano
  • Nirmala Gonsalves
Original Article



Eosinophilic gastritis (EG) and eosinophilic gastroenteritis (EGE) are chronic immune-mediated conditions of the digestive tract, which affect the stomach only, or the stomach and small intestines, respectively. Though these disorders are uncommon, they are being increasingly recognized and diagnosed. While health-related quality of life (HRQOL) has been evaluated in other eosinophilic gastrointestinal diseases, this study is the first to describe HRQOL impacts unique to EG/EGE.


This study aims to qualitatively describe experiences of adults diagnosed with EG and EGE. We aim to identify impacts on HRQOL in this population in order to inform clinical care and assessment.


Seven patients diagnosed with EG or EGE participated in semi-structured interviews assessing common domains of HRQOL.


Four distinct themes emerged from qualitative analyses, which represent impacts to HRQOL: the psychological impact of the diagnosis, impact on social relationships, financial impact, and impact on the body. These generally improved over time and with effective treatment.


This study demonstrated that patients with EG/EGE experience impacts to HRQOL, some of which differ from HRQOL of other eosinophilic gastrointestinal diseases. These results support the development of a disease-specific measure, or adaptation of an existing measure, to assess HRQOL in EG/EGE.


Eosinophilic gastritis Eosinophilic gastroenteritis Health-related quality of life Patient-reported outcomes 



Ms. Craven and Ms. Guadagnoli are supported by the T32DK101363 Training Grant in GI Physiology and Psychology.

Compliance with ethical statements

Conflict of interest

The authors have nothing to disclose and no competing interests.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Gastroenterology and HepatologyNorthwestern University Feinberg School of MedicineChicagoUSA

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