Digestive Diseases and Sciences

, Volume 62, Issue 12, pp 3625–3626 | Cite as

Fecal Calprotectin in Monitoring the Disease Activity in Colonic Inflammatory Bowel Disease

  • Cong DaiEmail author
  • Min Jiang
  • Ming-jun Sun


Author’s contributions

CD, MJ, and M-JS wrote the paper. CD and M-JS had the original idea for the paper. All authors reviewed and approved the final draft of the paper.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.


  1. 1.
    Puolanne AM, Kolho KL, Alfthan H, Ristimaki A, Mustonen H, Farkkila M. Rapid fecal calprotectin test and symptom index in monitoring the disease activity in colonic inflammatory bowel disease. Dig Dis Sci. (Epub ahead of print). doi: 10.1007/s10620-017-4770-0.
  2. 2.
    Gecse KB, Brandse JF, van Wilpe, S et al. Impact of disease location on fecal calprotectin levels in Crohn’s disease. Scand J Gastroenterol. 2015;50:841–847.CrossRefPubMedGoogle Scholar
  3. 3.
    Ferreiro-Iglesias R, Barreiro-de Acosta M, Otero Santiago M, et al. Fecal calprotectin as predictor of relapse in patients with inflammatory bowel disease under maintenance infliximab therapy. J Clin Gastroenterol. 2016;50:147–151.CrossRefPubMedGoogle Scholar
  4. 4.
    Mooiweer E, Severs M, Schipper ME, et al. Low fecal calprotectin predicts sustained clinical remission in inflammatory bowel disease patients: a plea for deep remission. J Crohns Colitis. 2015;9:50–55.CrossRefPubMedGoogle Scholar
  5. 5.
    Gisbert JP, Bermejo F, Perez-Calle JL, et al. Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse. Inflamm Bowel Dis. 2009;15:1190–1198.CrossRefPubMedGoogle Scholar
  6. 6.
    Walkiewicz D, Werlin SL, Fish D, Scanlon M, Hanaway P, Kugathasan S. Fecal calprotectin is useful in predicting disease relapse in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2008;14:669–673.CrossRefPubMedGoogle Scholar
  7. 7.
    Lasson A, Stotzer PO, Ohman L, Isaksson S, Sapnara M, Strid H. The intra-individual variability of faecal calprotectin: A prospective study in patients with active ulcerative colitis. J Crohns Colitis. 2014;9:26–32.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  1. 1.Department of Gastroenterology, First Affiliated HospitalChina Medical UniversityShenyang CityChina

Personalised recommendations