Digestive Diseases and Sciences

, Volume 62, Issue 7, pp 1702–1712 | Cite as

Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment

  • Daniel Lew
  • Elham Afghani
  • Stephen PandolEmail author


This paper reviews the current status of our understanding of the epidemiology, diagnosis, and management of the continuum of pancreatic diseases from acute and recurrent acute pancreatitis to chronic pancreatitis and the diseases that are often linked with pancreatitis including diabetes mellitus and pancreatic cancer. In addition to reviewing the current state of the field, we identify gaps in knowledge that are necessary to address to improve patient outcomes in these conditions.


Chronic pancreatitis Acute recurrent pancreatitis Hereditary pancreatitis Cystic fibrosis Alcohol Smoking 


Compliance with ethical standards

Conflict of interest

This work was supported by the following US federal grants: CA163200, AA11999, DK098108, DoD PR140717P2, DK108314, DCP NWU2014-04-01, W81XWH-16-PRMRP-DA. Dr. Pandol is a founder of Avenzoar Pharmaceuticals and a consultant for Allergan and SunBiopharma. There is no information in this work representing a commercial conflict of interest. Dr. Lew and Dr. Afghani do not have any conflict of interests.


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Cedars-Sinai Medical CenterLos AngelesUSA

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