Digestive Diseases and Sciences

, Volume 62, Issue 4, pp 843–850 | Cite as

Endoscopic Radiofrequency Ablation of the Pancreas

  • Tarun RustagiEmail author
  • Ankit Chhoda


Radiofrequency ablation (RFA) is a well-established technique to ablate dysplastic and neoplastic tissue via local thermal coagulative necrosis. Despite the widespread use in management of several cancers, the application of RFA in pancreas has been limited due to the increased risks of complications from the increased sensitivity of pancreatic tissue to thermal injury and proximity to vascular and biliary structures. RFA has been successfully used during laparotomy for locally advanced pancreatic carcinoma but requires an invasive approach. Endoscopic ultrasound-guided RFA offers the best combination of excellent visualization, real-time imaging guidance, and precise localization with minimal invasiveness. Several animal and human studies have demonstrated the technical feasibility and safety of endoscopic RFA in the pancreas. This article provides a comprehensive review of endoscopic RFA in the management of pancreatic lesions.


RFA EUS Endoscopic ultrasound CTP Cryotherm Pancreatic cysts Insulinoma Pancreatic cancer Habib Pancreatic cystic lesion 


Compliance with ethical standards

Conflict of interest



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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Division of Gastroenterology and HepatologyUniversity of New MexicoAlbuquerqueUSA
  2. 2.Department of Internal MedicineWaterbury HospitalWaterburyUSA

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