Locally Advanced Intrahepatic Cholangiocarcinoma: Complete Pathologic Response to Neoadjuvant Chemotherapy Followed by Left Hepatic Trisectionectomy and Caudate Lobectomy
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Case Presentation and Evolution
A 67-year-old man was initially evaluated for progressive right upper quadrant pain of several months duration. He denied jaundice, acholic stools, nausea, vomiting, or pruritus. Past medical history included prostate cancer, cholelithiasis, appendicitis, hyperlipidemia, chronic lower back pain, mild hypertension, mild asthma, and gastroesophageal reflux disease. Past surgical history included prostatectomy, cholecystectomy, and appendectomy. Family history was remarkable for a brother with prostate cancer and a sister with breast cancer. The patient had a remote history of smoking and alcohol abuse. Physical examination revealed right upper quadrant tenderness but no hepatosplenomegaly. He had mild central obesity, but no stigmata of cirrhosis. Initial laboratory findings (complete blood count and comprehensive metabolic panel) were unremarkable.
KeywordsGemcitabine Portal Vein Embolization Biliary Tract Cancer Future Liver Remnant Intrahepatic Cholangiocarcinoma
Conflict of interest
- 4.Farges O, Fuks D, Boleslawski E et al. Influence of surgical margins on outcome in patients with intrahepatic cholangiocarcinoma: a multicenter study by the AFC-IHCC-2009 study group. Ann Surg. 2011;254:824–829; discussion 830.Google Scholar