Digestive Diseases and Sciences

, Volume 60, Issue 11, pp 3226–3229 | Cite as

Locally Advanced Intrahepatic Cholangiocarcinoma: Complete Pathologic Response to Neoadjuvant Chemotherapy Followed by Left Hepatic Trisectionectomy and Caudate Lobectomy

  • Thuy B. Tran
  • Chinmaya K. Bal
  • Kurt Schaberg
  • Teri A. Longacre
  • Bhupinder S. Chatrath
  • George A. Poultsides
Stanford Multidisciplinary Seminars

Case Presentation and Evolution

A 67-year-old man was initially evaluated for progressive right upper quadrant pain of several months duration. He denied jaundice, acholic stools, nausea, vomiting, or pruritus. Past medical history included prostate cancer, cholelithiasis, appendicitis, hyperlipidemia, chronic lower back pain, mild hypertension, mild asthma, and gastroesophageal reflux disease. Past surgical history included prostatectomy, cholecystectomy, and appendectomy. Family history was remarkable for a brother with prostate cancer and a sister with breast cancer. The patient had a remote history of smoking and alcohol abuse. Physical examination revealed right upper quadrant tenderness but no hepatosplenomegaly. He had mild central obesity, but no stigmata of cirrhosis. Initial laboratory findings (complete blood count and comprehensive metabolic panel) were unremarkable.

Computed tomography (CT) revealed a dominant 8.5-cm left-sided liver lesion with a satellite lesion...


Gemcitabine Portal Vein Embolization Biliary Tract Cancer Future Liver Remnant Intrahepatic Cholangiocarcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflict of interest



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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Thuy B. Tran
    • 1
  • Chinmaya K. Bal
    • 1
  • Kurt Schaberg
    • 2
  • Teri A. Longacre
    • 2
  • Bhupinder S. Chatrath
    • 3
  • George A. Poultsides
    • 1
  1. 1.Department of SurgeryStanford University School of MedicineStanfordUSA
  2. 2.Department of PathologyStanford University School of MedicineStanfordUSA
  3. 3.Department of MedicineSequoia Regional Cancer CenterVisaliaUSA

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