Digestive Diseases and Sciences

, Volume 59, Issue 9, pp 2236–2242

Do We Need Colonoscopy Following Acute Diverticulitis Detected on Computed Tomography to Exclude Colorectal Malignancy?

  • Young Hoon Choi
  • Seong-Joon Koh
  • Ji Won Kim
  • Byeong Gwan Kim
  • Kook Lae Lee
  • Jong Pil Im
  • Joo Sung Kim
  • Hyun Chae Jung
Original Article

DOI: 10.1007/s10620-014-3151-1

Cite this article as:
Choi, Y.H., Koh, SJ., Kim, J.W. et al. Dig Dis Sci (2014) 59: 2236. doi:10.1007/s10620-014-3151-1

Abstract

Background

Although colonoscopy verification is warranted after an acute event of diverticulitis to exclude underlying malignancy, little evidence is available to support the recommendations.

Aim

The aim of this study was to examine whether subsequent colonoscopy is warranted in patients with diverticulitis on computed tomography (CT).

Methods

The study was composed of patients diagnosed with acute diverticulitis on CT scan from January 2001 to March 2013. Patients who had subsequent colonoscopy within a year from the date of CT were included. For each diverticulitis case, two age- (±5 years) and sex-matched controls were identified from healthy individuals who had received screening colonoscopy. We evaluated the diagnostic yield of advanced colonic neoplasia in colonoscopy.

Results

One hundred and forty-nine patients underwent subsequent colonoscopy within a year from the date of CT. Among the patients, 11 (7.4 %) had colon cancer and 5 (3.4 %) had advanced adenoma. A case–control study revealed that the odds of detecting an advanced neoplasia among patients with diverticulitis on CT were approximately 8.8 times greater than in the age- and sex-matched controls [OR 8.84; 95 % CI 2.90–26.96; p < 0.001]. On analysis of the diverticulitis group, age (≥50 years) is an independent risk factor for detecting advanced colonic neoplasia.

Conclusions

The yield of advanced colonic neoplasia was substantially higher in patients with acute diverticulitis than in asymptomatic, average-risk individuals. Colonoscopy verification is warranted in patients with diverticulitis detected on CT, especially in those aged 50 years or older.

Keywords

Diverticulitis Colonoscopy Adenoma Colon cancer 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Young Hoon Choi
    • 1
  • Seong-Joon Koh
    • 2
  • Ji Won Kim
    • 2
  • Byeong Gwan Kim
    • 2
  • Kook Lae Lee
    • 2
  • Jong Pil Im
    • 1
  • Joo Sung Kim
    • 1
  • Hyun Chae Jung
    • 1
  1. 1.Department of Internal Medicine, Liver Research InstituteSeoul National University College of MedicineSeoulKorea
  2. 2.Department of Internal Medicine, Seoul National University Boramae HospitalSeoul National University College of MedicineSeoulKorea

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