Isolated Russell Body Duodenitis
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Under the influence of an antigen, plasma cells produce immunoglobulins, which appear as eosinophilic globules on light microscopy. Sometimes, one or more of the cisterns of rough endoplasmic reticulum in plasma cells may become distended with these immunoglobulin-containing inclusions, termed Russell bodies, which were first described in 1890 by W. Russell . These bodies are probably a result of disturbed secretion . Mott cells are plasma cells containing multiple Russell bodies. Mott cells can be found in numerous settings, including: multiple myeloma, indolent lymphomas, and in the setting of chronic inflammation. Therefore, their presence alone is not indicative of malignancy.
Russell body gastritis (RBG), a localized collection of polyclonal Russell bodies in the stomach, is an uncommon, yet well-reported entity that is often associated with Helicobacter pylori infection [3, 4]. It was first described in 1998 in Japan by Tazawa and Tsutsumi . They reported a...
KeywordsRussell body Helicobacter pylori Gastritis Duodenitis
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