Digestive Diseases and Sciences

, Volume 55, Issue 5, pp 1320–1324 | Cite as

Erosive Esophagitis in Asymptomatic Subjects: Risk Factors

  • Fu-Wei Wang
  • Ming-Shium Tu
  • Hung-Yi Chuang
  • Hsien-Chung Yu
  • Lung-Chih Cheng
  • Ping-I Hsu
Original Article



Asymptomatic erosive esophagitis is a common yet rarely reported disease. The purpose of this study is to investigate the prevalence of asymptomatic erosive esophagitis and to identify the risk factors for this disease.

Materials and Methods

In this study, we investigated 572 asymptomatic subjects undergoing health check-ups after upper gastrointestinal endoscopy. The severity of esophagitis was evaluated by the Los Angeles classification, and the independent risk factors for asymptomatic esophagitis were analyzed by the logistic regression method.


The results showed the prevalence of erosive esophagitis in asymptomatic subjects was 12% (70/572). In all asymptomatic subjects, erosive esophagitis was grade A (71%) or B (29%). Univariate analysis revealed that male gender, high body mass index (BMI), and consumption of tobacco, alcohol, tea, spicy foods, and betel nut were associated with the development of erosive esophagitis. Multivariate analysis revealed that male gender (OR, 3.8, 95% CI, 1.5–9.3) and high BMI (BMI 25–30: OR, 2.3, 95% CI, 1.3–4.2; BMI >30: OR, 3.8, 95% CI, 1.3–10.9) were independent predictors of erosive esophagitis.


Our data revealed male gender and high BMI are independent risk factors for asymptomatic erosive esophagitis.


Erosive esophagitis Asymptomatic Endoscopy Health check-up 


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Fu-Wei Wang
    • 1
  • Ming-Shium Tu
    • 1
  • Hung-Yi Chuang
    • 2
    • 3
  • Hsien-Chung Yu
    • 4
  • Lung-Chih Cheng
    • 4
  • Ping-I Hsu
    • 4
  1. 1.Department of Family MedicineKaohsiung Veterans General HospitalKaohsiungTaiwan
  2. 2.Department of Community MedicineKaohsiung Medical University HospitalKaohsiungTaiwan
  3. 3.Faculty of Public HealthKaohsiung Medical UniversityKaohsiungTaiwan
  4. 4.Division of Gastroenterology, Department of Internal MedicineKaohsiung Veterans General HospitalKaohsiungTaiwan

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