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Digestive Diseases and Sciences

, Volume 52, Issue 10, pp 2884–2887 | Cite as

Age and Indication for Referral to Capsule Endoscopy Significantly Affect Small Bowel Transit Times: The Given Database

  • Zvi Fireman
  • Yael Kopelman
  • Shosh Friedman
  • Hagit Ephrath
  • Eran Choman
  • Hila Debby
  • Rami Eliakim
Original Article

Abstract

The purpose of this study was to examine the effect of age and selected indications for capsule endoscopy on small bowel transit times. Data on 67 clinical studies (790 subjects with different gastrointestinal pathologies [49.5% males; mean age, 51.9 ± 18.33 years; range, 18–91 years] and 87 healthy volunteers) were retrieved from the company (Given Imaging, Ltd.)-sponsored database. All subjects swallowed the PillCam SB Capsule after a 12-hr fast. The capsule reached the cecum in all 877 participants. Indications for referral for capsule endoscopy were as follows: 372 obscure gastrointestinal bleeding, 96 suspected Crohn’s disease, 65 celiac disease, 54 irritable bowel syndrome, and 116 familial adenomatous polyposis, intestinal lymphoma, or ulcerative colitis. One group consisted of patients <40 years old (n = 235), and the other patients 40 years old (n = 555). The younger group, volunteers, and Crohn’s disease patients had significantly shorter small bowel transit times than the others (P < 0.001). Gastric emptying indirectly influenced capsule transit time.

Keywords

Capsule endoscopy Small bowel transit time Gastrointestinal pathologies Gastric emptying Age Gender 

Notes

Acknowledgment

Esther Eshkol is thanked for editorial assistance.

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Zvi Fireman
    • 1
    • 2
  • Yael Kopelman
    • 1
    • 2
  • Shosh Friedman
    • 3
  • Hagit Ephrath
    • 3
  • Eran Choman
    • 3
  • Hila Debby
    • 3
  • Rami Eliakim
    • 2
    • 4
  1. 1.Department of GastroenterologyHillel Yaffe Medical CenterHaderaIsrael
  2. 2.Bruce Rapaport Faculty of MedicineThe TechnionHaifaIsrael
  3. 3.Given Imaging, Ltd.YoqneamIsrael
  4. 4.Department of GastroenterologyRambam Medical CenterHaifaIsrael

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