Digestive Diseases and Sciences

, Volume 53, Issue 9, pp 2474–2479

The Clinical Picture of Uncomplicated Versus Complicated Diverticulitis of the Colon

  • Antonio Tursi
  • Giovanni Brandimarte
  • GianMarco Giorgetti
  • Walter Elisei
  • Michele Maiorano
  • Fabio Aiello
Original Paper

DOI: 10.1007/s10620-007-0161-2

Cite this article as:
Tursi, A., Brandimarte, G., Giorgetti, G. et al. Dig Dis Sci (2008) 53: 2474. doi:10.1007/s10620-007-0161-2

Abstract

Purpose There is no consensus about the correct definition of uncomplicated diverticulitis (UD) in clinical practice. We evaluated therefore whether clinical picture of UD differs from complicated diverticulitis (CD). Fifty consecutive eligible patients (21 males, 29 females, mean age 63.6 years, range 47–75 years) were studied. Symptoms, the inflammatory indices, and Computerized Tomography (CT) scan of the abdomen were assessed at the time of admission. Results Thirty-nine patients classified were affected by UD and 11 patients by CD. CD patients showed more severe clinical picture than UD and required urgent Hospital admission. Conversely, most of the patients affected by UD were treated as outpatients. CD patients showed higher symptom scores than UD patients, except the parameter “diarrhea”. All CD patients showed increases in all inflammatory indices. Conversely, all UD patients showed increased ESR, CRP and fibrinogen, but WBC and α1-acid glycoprotein were increased in only a few cases. CT scan in CD patients always showed signs of severe colonic and pericolonic inflammation. Conversely, UD patients often showed moderate localized signs of inflammation without complication. Conclusions Clinical, laboratory, and radiological findings may easily differentiate uncomplicated from complicated diverticulitis of the colon. This integrated approach may be helpful in clinical settings.

Keywords

Complicated diverticulitis Endoscopy Laboratory Radiology Uncomplicated diverticulitis 

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Antonio Tursi
    • 1
  • Giovanni Brandimarte
    • 2
  • GianMarco Giorgetti
    • 3
  • Walter Elisei
    • 2
  • Michele Maiorano
    • 4
  • Fabio Aiello
    • 5
  1. 1.Digestive Endoscopy Unit“Lorenzo Bonomo” HospitalAndriaItaly
  2. 2.Department of Internal Medicine, Division of Gastroenterology“Cristo Re” HospitalRomeItaly
  3. 3.Clinical Nutrition Unit“S. Eugenio” HospitalRomeItaly
  4. 4.Department of Radiology“Lorenzo Bonomo” HospitalAndriaItaly
  5. 5.Department of Quantitative Methods for Human SciencesUniversity of PalermoPalermoItaly

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