Digestive Diseases and Sciences

, Volume 52, Issue 12, pp 3521–3523 | Cite as

Postinfantile Giant Cell Hepatitis Due to Hepatitis E Virus Along with the Presence of Autoantibodies

  • Özgür Harmanci
  • İbrahim Koral Önal
  • Osman Ersoy
  • Bora Gürel
  • Cenk Sökmensüer
  • Yusuf Bayraktar
Original Paper

Keywords

Giant cell hepatitis Hepatitis E virus 

References

  1. 1.
    Johnson SJ, Mathew J, MacSween RN, Bennett MK, Burt AD (1994) Post-infantile giant cell hepatitis: histological and immunohistochemical study. J Clin Pathol 47:1022–1027PubMedCrossRefGoogle Scholar
  2. 2.
    Phillips MJ, Blendis LM, Poucell S, et al. (1991) Syncytial giant-cell hepatitis. Sporadic hepatitis with distinctive pathological features, a severe clinical course, and paramyxoviral features. N Engl J Med 324:455–460PubMedCrossRefGoogle Scholar
  3. 3.
    Kuntzen T, Friedrichs N, Fischer HP, Eis-Hubinger AM, Sauerbruch T, Spengler U (2005) Postinfantile giant cell hepatitis with autoimmune features following a human herpesvirus 6-induced adverse drug reaction. Eur J Gastroenterol Hepatol 17:1131–1134PubMedCrossRefGoogle Scholar
  4. 4.
    Thijs JC, Bosma A, Henzen-Logmans SC, Meuwissen SG (1985) Postinfantile giant cell hepatitis in a patient with multiple autoimmune features. Am J Gastroenterol 80:294–297PubMedGoogle Scholar
  5. 5.
    Spichtin HP, Gudat F, Schmid M, Pirovino M, Altorfer J, Bianchi L (1982) Microtubular aggregates in human chronic non-A, non-B hepatitis with bridging hepatic necrosis and multinucleated hepatocytic giant cells. Liver 2:355–360PubMedGoogle Scholar
  6. 6.
    Alvarez F, Berg PA, Bianchi FB, et al. (1999) International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 31:929–938PubMedCrossRefGoogle Scholar
  7. 7.
    Montgomery CK, Ruebner BH (1976) Neonatal hepatocellular giant cell transformation: a review. Perspect Pediatr Pathol 3:85–101PubMedGoogle Scholar
  8. 8.
    Aterman K (1963) Neonatal hepatitis and its relation to viral hepatitis of mother—a review of the problem. Am J Dis Child 105:395–416PubMedGoogle Scholar
  9. 9.
    Tordjmann T, Grimbert S, Genestie C, Freymuth F, Guettier C, Callard P, Trinchet JC, Beaugrand M (1998) Adult multi-nuclear cell hepatitis. A study in 17 patients. Gastroenterol Clin Biol 22:305–310PubMedGoogle Scholar
  10. 10.
    Gorelik M, Debski R, Frangoul H (2004) Autoimmune hemolytic anemia with giant cell hepatitis: case report and review of the literature. J Pediatr Hematol Oncol 26:837–839PubMedGoogle Scholar
  11. 11.
    Lau JY, Koukoulis G, Mieli-Vergani G, Portmann BC, Williams R (1992) Syncytial giant-cell hepatitis—a specific disease entity? J Hepatol 15:216–219PubMedCrossRefGoogle Scholar
  12. 12.
    Worm HC, Van Der Poel WH, Brandstatter G (2002) Hepatitis E: an overview. Microbes Infect 4:657–666PubMedCrossRefGoogle Scholar
  13. 13.
    Tan CR, Bao ZY, Sun HY, Hu M, Chen Y, Chen M, Zhang M (2005) Serological antibodies comparison of a hepatitis E outbreak. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 19:35–38PubMedGoogle Scholar
  14. 14.
    Devaney K, Goodman ZD, Ihsak KG (1992) Postinfantile giant-cell transformation in hepatitis. Hepatology 16:327–333PubMedCrossRefGoogle Scholar
  15. 15.
    Kammer AR, van der Burg SH, Grabscheid B, Hunziker IP, Kwappenberg KM, Reichen J, Melief CJ, Cerny A (1999) Molecular mimicry of human cytochrome P450 by hepatitis C virus at the level of cytotoxic T cell recognition. J Exp Med 190:169–176PubMedCrossRefGoogle Scholar
  16. 16.
    Bianchi L, Terracciano LM (1994) Giant cell hepatitis in adults. Schweiz Rundsch Med Prax 83:1237–1241PubMedGoogle Scholar
  17. 17.
    Nagasaki F, Ueno Y, Mano Y, Igarashi T, Yahagi K, Niitsuma H, Okamoto H, Shimosegawa T (2005) A patient with clinical features of acute hepatitis E viral infection and autoimmune hepatitis. Tohoku J Exp Med 206:173–179PubMedCrossRefGoogle Scholar
  18. 18.
    Nagasaki F, Ueno Y, Kanno N, Okamoto H, Shimosegawa T (2005) A case of acute hepatitis with positive autoantibodies who actually had hepatitis E virus infection. Hepatol Res (Epub ahead of print)Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Özgür Harmanci
    • 1
  • İbrahim Koral Önal
    • 2
    • 4
  • Osman Ersoy
    • 1
  • Bora Gürel
    • 3
  • Cenk Sökmensüer
    • 3
  • Yusuf Bayraktar
    • 1
  1. 1.Department of Internal Medicine, Gastroenterology DivisionHacettepe University Medical SchoolAnkaraTurkey
  2. 2.Department of Internal MedicineHacettepe University Medical SchoolAnkaraTurkey
  3. 3.Department of PathologyHacettepe University Medical SchoolAnkaraTurkey
  4. 4.Hacettepe üniversitesi tip fakültesi hastanesigastroenteroloji ünitesi, SihhiyeAnkaraTürkiye

Personalised recommendations