Advertisement

Digestive Diseases and Sciences

, Volume 52, Issue 3, pp 679–680 | Cite as

An Unusual Case Report of Small Bowel Candida Overgrowth as a Cause of Diarrhea and Review of the Literature

  • Mark FriedmanEmail author
  • David B. Ramsay
  • Marie L. Borum
Letter to the Editor

Introduction

Candida overgrowth causing diarrhea is rare. There are only a few reported cases of individuals with underlying malignancy, severe immunocompromise, on immunosuppressive therapy or on recent antibiotic therapy who have had Candida-induced diarrhea. It is unclear if individuals without these recognized conditions can have an overgrowth of Candida species in the small bowel resulting in diarrhea. This report is a rare case of an immunocompetent individual with noninvasive small-bowel candidiasis presenting with diarrhea. We also offer a review of the literature.

Case report

A 61-year-old man with a past medical history significant for hepatitis C, hypertension, insulin-dependent diabetes, and chronic diarrhea presented to George Washington University Hospital complaining of one week of worsening diarrhea and severe bilateral lower-extremity pain. The patient reported that he had a one-year history of chronic diarrhea. During the week before admission, the diarrhea worsened...

Keywords

Diarrhea Candida Celiac Disease Chronic Diarrhea Lactase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Kane JG, Chretien JH, Garagusi VF (1976) Diarrhea caused by Candida. Lancet 1:335–336PubMedCrossRefGoogle Scholar
  2. 2.
    Gupta TP, Ehrinpreis MN (1990) Candida-associated diarrhea in hospitalized patients. Gastroenterology 98:780–785PubMedGoogle Scholar
  3. 3.
    Joshi SN, Garvin PJ, Sunwoo YC (1981) Candidiasis of the duodenum and jejunum. Gastroenterology 80:829–833PubMedGoogle Scholar
  4. 4.
    Strober W, Krakauer R, Klaeveman HL, Reynolds HY, Nelson DL (1976) Secretory component deficiency. A disorder of the IgA immune system. N Engl J Med 294:351–356PubMedCrossRefGoogle Scholar
  5. 5.
    Chretien JH, Garagusi VF (1982) Current management of fungal enteritis. Med Clin North Am 66:675–678PubMedGoogle Scholar
  6. 6.
    Cipollini F, Altilia F (1981) Candidiasis of the small intestine. Gastroenterology 81:825–826PubMedGoogle Scholar
  7. 7.
    Berman DA, Sobieski RJ (1977) Depression of lactose hydrolysis by yeasts. J Med Microbiol 10:373–376PubMedCrossRefGoogle Scholar
  8. 8.
    Burke V, Gracey M (1980) An experimental model of gastrointestinal candidiasis. J Med Microbiol 13:103–110PubMedCrossRefGoogle Scholar
  9. 9.
    Thelen P, Burke V, Gracey M (1978) Effects of intestinal microorganisms on fluid and electrolyte transport in the jejunum of the rat. J Med Microbiol 11:463–470PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Mark Friedman
    • 1
    Email author
  • David B. Ramsay
    • 1
  • Marie L. Borum
    • 1
  1. 1.Division of Gastroenterology and Liver DiseasesGeorge Washington University School of MedicineWashingtonUSA

Personalised recommendations