Digestive Diseases and Sciences

, Volume 52, Issue 12, pp 3316–3320 | Cite as

Sarcoidosis of Gastrointestinal Tract: A Rare Disease

  • Bobbak Vahid
  • Maya Spodik
  • Kristine N. Braun
  • Leyla J. Ghazi
  • Ali Esmaili
Review Article


Gastrointestinal (GI) tract sarcoidosis is an uncommon form of sarcoidosis. The GI tract can be involved as an isolated disease as a part of systemic sarcoidosis. Clinical manifestations of esophageal, gastric, small bowel, colon, and appendicular sarcoidosis are discussed in this review. The differential diagnosis of GI sarcoidosis is extensive. Other granulomatous diseases of the GI tract, like tuberculosis, fungal infections, parasitic diseases, inflammatory bowel disease, and Whipple’s disease, should be excluded before making the diagnosis of GI sarcoidosis. Corticosteroid therapy is effective in treatment of GI sarcoidosis. Surgical intervention may be necessary in patients with bowel obstruction, perforation, or massive hemorrhage.


Gastrointestinal sarcoidosis Esophageal sarcoidosis Gastric sarcoidosis Intestinal sarcoidosis Extrapulmonary sarcoidosis 


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Bobbak Vahid
    • 1
  • Maya Spodik
    • 2
  • Kristine N. Braun
    • 2
  • Leyla J. Ghazi
    • 2
  • Ali Esmaili
    • 2
  1. 1.Department of Pulmonary and Critical Care MedicineThomas Jefferson University HospitalPhiladelphiaUSA
  2. 2.Department of MedicineThomas Jefferson University HospitalPhiladelphiaUSA

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