Nocturnal Hydration—An Effective Modality to Reduce Recurrent Abdominal Pain and Recurrent Pancreatitis in Patients with Adult-Onset Cystic Fibrosis
- First Online:
- 67 Downloads
Recurrent abdominal pain and recurrent pancreatitis are common problems associated with some patients with cystic fibrosis (CF). There is no known effective method to prevent recurrent abdominal pain and recurrent pancreatitis in such patients. The objective of this study was to determine whether nocturnal hydration (NH) prevents recurrent abdominal pain and recurrent acute pancreatitis in patients with adult-onset CF. Adult CF patients who were referred to our Pancreatic Diseases Clinic for recurrent abdominal pain and pancreatitis were enrolled in the study. Each patient was encouraged to drink plenty of water during the night and established a 6-month diary (3 months before and 3 months after NH was initiated), recording the frequency and severity of their abdominal pain, the amount of pain medication taken, and the volume of their water intake. We also reviewed the number of doctor's clinic visits, emergency room visits, and hospitalizations for about 1 year before and 1 year after the initiation of the NH. The frequency and the severity of abdominal pain in this group of patients were significantly reduced. The amount of pain medication and the number of emergency room visits and hospitalizations for abdominal pain and acute pancreatitis were reduced. NH is a simple and cost-effective method to prevent recurrent abdominal pain and pancreatitis in patients with adult-onset CF.
KeywordsNocturnal hydration Cystic fibrosis Recurrent pancreatitis.
- 4.Liddle RA, Cohn JA (1995) Hereditary diseases of the pancreas. In: Yamada T, et al. (eds) Textbook of gastroenterology, 2nd edn. Lippincott Williams & Wlikins, Philadelphia, PA, pp 2161– 2173Google Scholar
- 5.Rosner B (2000) Fundamentals of biostatistics, 5th edn. Duxbury Press, Pacific Grove, CAGoogle Scholar
- 24.Gelrud A, Sheth S, Banerjee S, Weed D, Shea J, Chuttani R, Howell DA, Telford JJ, Carr-Locke DL, Regan MM, Ellis L, Durie PR, Freedman SD (2004) Analysis of cystic fibrosis gene product (CFTR) function in patients with pancreatic divisum and recurrent acute pancreatitis. Am J Gastroenterol 99:1557–1562PubMedCrossRefGoogle Scholar