Digestive Diseases and Sciences

, Volume 52, Issue 11, pp 3296–3297 | Cite as

Hypercalcemic Encephalopathy in a Patient with Hepatocellular Carcinoma

  • Pere Tudela
  • Berta Soldevila
  • Josep Maria Mòdol
  • Eugeni Domènech
Original Paper


Cirrhotic patients with hepatocellular carcinoma (HCC) frequently develop hepatic encephalopathy. Metabolic etiology of encephalopathy is less often considered in these patients. Although paraneoplastic hypercalcemia may be associated with several malignant tumors, it has also been described in HCC [1, 2, 3, 4], and may cause neurologic disturbances. We present a case of hypercalcemic encephalopathy in a patient with hepatic cirrhosis and underlying HCC in whom first diagnostic was hepatic encephalopathy.


Tamoxifen Hepatic Encephalopathy Hypercalcemia Primary Hyperparathyroidism Ascitic Fluid 
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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Pere Tudela
    • 1
  • Berta Soldevila
    • 2
  • Josep Maria Mòdol
    • 1
  • Eugeni Domènech
    • 3
  1. 1.Unitat de Curta EstadaEmergency Unit, Hospital Universitari Germans Trias i Pujol, BadalonaCataloniaSpain
  2. 2.Endocrinology DepartmentHospital Universitari Germans Trias i Pujol, BadalonaCataloniaSpain
  3. 3.Eugeni Domènech, Gastroenterology Department5a planta, edifici general, Hospital Universitari Germans Trias i PujolBadalonaSpain

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