Digestive Diseases and Sciences

, Volume 51, Issue 3, pp 454–460 | Cite as

Prevalence of Irritable Bowel Syndrome and Depression in Fibromyalgia

  • Jayde E. Kurland
  • Walter J. Coyle
  • Anne Winkler
  • Elizabeth Zable
Intestinal Diseases and Irritable Bowel Syndrome

Abstract

The purpose of this study was to determine the point prevalence of depressive symptoms, using the PRIME-MD questionnaire, and irritable bowel syndrome (IBS), while comparing the Rome II to the Rome I criteria, in patients with fibromyalgia (FM) and rheumatologic controls in an outpatient setting. The prevalence of IBS in FM patients (n = 105) was 63% by Rome I and 81% by Rome II criteria. The prevalence of IBS in controls (n = 62) was 15% by Rome I and 24% by Rome II criteria (FM vs. control; P < 0.001). Depressive symptoms were met in 40% of FM patients and 8% of controls (P < 0.001). The coexistence of IBS and depressive symptoms in the FM patients was 31% (Rome I) and 34% (Rome II). The prevalence of IBS and depressive symptoms was higher in FM patients compared to the control population. Identification of IBS and depressive symptoms in FM patients might enable clinicians to better meet the needs of this patient population.

Key Words

fibromyalgia irritable bowel syndrome depression Rome I criteria Rome II criteria 

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References

  1. 1.
    Offenbaecher M, Glatzeder K, Ackenheil M: Self-reported depression, familial history of depression and fibromyalgia (FM), and psychological distress in patients with FM. Z Rheumatol 57 (Suppl 2):94–96, 1998CrossRefPubMedGoogle Scholar
  2. 2.
    Burckhardt CS, O’Reilly CA, Wiens AN, Clark SR, Campbell SM, Bennett RM: Assessing depression in fibromyalgia patients. Arthritis Care Res 7:35–39, 1994PubMedGoogle Scholar
  3. 3.
    Vanner SJ, Depew WT, Paterson WG, et al.: Predictive value of the rome criteria for diagnosing the irritable bowel syndrome. Am J Gastroenterol 94:2912–2917, 1999CrossRefPubMedGoogle Scholar
  4. 4.
    Pace F, Sarzi-Puttini P, Manzionna G: Visceral hypersensitivity is not a feature of fibromyalgia syndrome. J Musculoskel Pain 9:47–55, 2001CrossRefGoogle Scholar
  5. 5.
    Sperber AD, Atzmon Y, Neumann L, et al.: Fibromyalgia in the irritable bowel syndrome: Studies of prevalence and clinical implications. Am J Gastroenterol 94:3541–3546, 1999CrossRefPubMedGoogle Scholar
  6. 6.
    Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA: Functional bowel disorders and functional abdominal pain. Gut 45 (Suppl 2):II43–II47, 1999PubMedGoogle Scholar
  7. 7.
    Ercolani M, Trombini G, Chattat R, et al.: Fibromyalgic syndrome: Depression and abnormal illness behavior. multicenter investigation. Psychother Psychosom 61:178–186, 1994PubMedGoogle Scholar
  8. 8.
    Spitzer RL, Kroenke K, Williams JB: Validation and utility of a self-report version of PRIME-MD: The PHQ primary care study. Primary care evaluation of mental disorders. Patient health questionnaire. JAMA 282:1737–1744, 1999CrossRefPubMedGoogle Scholar
  9. 9.
    Wolfe F, Smythe HA, Yunus MB, et al.: The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. report of the multicenter criteria committee. Arth Rheum 33:160–172, 1990Google Scholar
  10. 10.
    Thompson WG, Dotevall G, Drossman DA, Heaton KW: Irritable bowel syndrome: Guidelines for the diagnosis and functional abdominal pain. Gastroenterol Int 2:92–95, 1989Google Scholar
  11. 11.
    Triadafilopoulos G, Simms RW, Goldenberg DL: Bowel dysfunction in fibromyalgia syndrome. Dig Dis Sci 36:59–64, 1991PubMedGoogle Scholar
  12. 12.
    Drossman DA, Sandler RS, McKee DC, Lovitz AJ: Bowel patterns among subjects not seeking health care. use of a questionnaire to identify a population with bowel dysfunction. Gastroenterology 83:529–534, 1982PubMedGoogle Scholar
  13. 13.
    Mearin F, Roset M, Badia X, et al.: Splitting irritable bowel syndrome: From original Rome to Rome II criteria. Am J Gastroenterol 99:122–130, 2004PubMedGoogle Scholar
  14. 14.
    Mearin F, Balboa A, Badia X, et al.: Irritable bowel syndrome subtypes according to bowel habit: Revisiting the alternating subtype. Eur J Gastroenterol Hepato 115:165–172, 2003Google Scholar
  15. 15.
    Katon W, Schulberg H: Epidemiology of depression in primary care. Gen Hosp Psychiatry 14:237–247, 1992PubMedGoogle Scholar
  16. 16.
    Rush J, Hay B: Depression guideline panel: Depression in primary care, detection and diagnosis, clinical practice guideline. AHCPR 1, 1993Google Scholar
  17. 17.
    Abdel-Nasser AM, Abd El-Azim S, Taal E, El-Badawy SA, Rasker JJ, Valkenburg HA: Depression and depressive symptoms in rheumatoid arthritis patients: An analysis of their occurrence and determinants. Br J Rheumatol 37:391–397, 1998CrossRefPubMedGoogle Scholar
  18. 18.
    Soderlin MK, Hakala M, Nieminen P: Anxiety and depression in a community-based rheumatoid arthritis population. Scand J Rheumatol 29:177–183, 2000PubMedGoogle Scholar
  19. 19.
    Boyce PM, Koloski NA, Talley NJ: Irritable bowel syndrome according to varying diagnostic criteria: Are the new rome II criteria unnecessarily restrictive for research and practice? Am J Gastroenterol 95:3176–3183, 2000PubMedGoogle Scholar
  20. 20.
    Giesecke T, Williams DA, Harris RE, et al.: Subgrouping of fibromyalgia patients on the basis of pressure-pain thresholds and psychological factors. Arth Rheum 48:2916–2922, 2003Google Scholar
  21. 21.
    Chang L: The association of functional gastrointestinal disorders and fibromyalgia. Eur J Surg Suppl 583:32–36, 1998PubMedGoogle Scholar
  22. 22.
    Mertz H, Morgan V, Tanner G, et al.: Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention. Gastroenterology 118:842–848, 2000CrossRefPubMedGoogle Scholar
  23. 23.
    Silverman DH, Munakata JA, Ennes H, Mandelkern MA, Hoh CK, Mayer EA: Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology 112:64–72, 1997CrossRefPubMedGoogle Scholar
  24. 24.
    Chang L, Berman S, Mayer EA, et al.: Brain responses to visceral and somatic stimuli in patients with irritable bowel syndrome with and without fibromyalgia. Am J Gastroenterol 98:1354–1361, 2003CrossRefPubMedGoogle Scholar
  25. 25.
    Pimentel M, Wallace D, Hallegua D, et al.: A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing. Ann Rheum Dis 63:450–452, 2004CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science + Business Media, Inc. 2006

Authors and Affiliations

  • Jayde E. Kurland
    • 1
    • 4
  • Walter J. Coyle
    • 1
  • Anne Winkler
    • 2
  • Elizabeth Zable
    • 3
  1. 1.Department of GastroenterologyNaval Medical Center San DiegoSan Diego
  2. 2.St. John’s Physicians and ClinicsSpringfield
  3. 3.University Community HospitalTampaUSA
  4. 4.Rockville

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