Advertisement

Digestive Diseases and Sciences

, Volume 49, Issue 11–12, pp 1986–1989 | Cite as

Case Report: Sirolimus Therapy in Orthotopic Liver Transplant (OLT) Recipients with Acute Renal Insufficiency

  • Marzia Montalbano
  • Guy W. NeffEmail author
  • Grabriella Slapak-Green
  • Thierry Berney
  • Douglas Meyer
Article
orthotopic Liver Transplantation calcineurin inhibitor sirolimus 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Falkenhain ME, Cosio FG, Sedmak DD: Progressive histologic injury in kidneys from heart and liver transplant recipients receiving cyclosporine. Transplantation 62:364–370, 1996CrossRefGoogle Scholar
  2. 2.
    Grinyo JM, Gil-Vernet S, Seron D, Hueso M, Fulladosa X, Cruzado Moreso F, Fernandez A, Torras J, Riera L, Castelao AM, Alsina J: Primary immunouppression with mycophenolate mofetil and antithymocyte globin for kidney transplant recipients of a suboptimal graft. Nephrol Dial Transplant 13:2061–2064, 1998CrossRefGoogle Scholar
  3. 3.
    MacDonal AS: Management strategies for nephrotoxicity. Transplantation 69:SS31–SS36, 2000Google Scholar
  4. 4.
    McDonald AS: Management strategies for nephrotoxicity. Transplantation 69:SS31–SS36, 2000CrossRefGoogle Scholar
  5. 5.
    Mihatsch MJ, Steiner K, Abeywickrama KH, Landmann J, Thiel G: Risk factors for the development of chronic cyclosporine-nephrotoxicity. Clin Nephrol 29:165–175, 1988PubMedGoogle Scholar
  6. 6.
    Monsour HP, Wood RP, Dyer CH, Galati JS, Ozaki CF, Clark JK: Renal insufficiency and hypertension as long-term complications in liver transplantation. Semin Liver Dis 15:123–132, 1995CrossRefGoogle Scholar
  7. 7.
    Murgia M, Jordan S, Kahan B: The side effects profile of sirolimus: A phase I study in quiescent cyclosporine-prednisolone-treated renal transplant patients. Kidney Int 49:209, 1996CrossRefGoogle Scholar
  8. 8.
    Platz KT, Mueller AR, Blumhardt G, Bachmann S, Bechestein WO, Kahl P, Neuhaus P: Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506 treated patients. Transplant Int 7:S52–S57, 1994CrossRefGoogle Scholar
  9. 9.
    Porayko MK, Wiesner RH, Hay JE, Krom RAF, Dickson ER, Beaver S, Schwerman L: Bone disease in liver transplant recipients: Incidence, timing and risk factors. Transplant Proc 23:1462–1465, 1991PubMedGoogle Scholar
  10. 10.
    Rimola A, Galver JS, Schade RR, el-Lankany S, Starzl TE, van Thiel DH: Effects of renal impairment on liver transplantation. Gastroenterology 93:148–156, 1987CrossRefGoogle Scholar
  11. 11.
    Ruiz P, Kolbeck PC, Scroggs MW, Sanfilippo F: Association between cyclosporine therapy and interstitial fibrosis in renal allograft biopsies. Transplantation 45:91–95, 1988CrossRefGoogle Scholar
  12. 12.
    Saeberg EC, et al.: Liver transplantation in the United States from 1987–1998: Update results from the UNOS Liver Transplant Registry. Clin Transplant 17–37, 1998Google Scholar
  13. 13.
    Watson CJE, Friend P, Jamieson NV, Frick TW, Alexander G, Gimson AE, Calne R: Sirolimus: A potent new immunosuppressant for liver transplantation. Transplantation 67:505–509, 1999CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2004

Authors and Affiliations

  • Marzia Montalbano
    • 1
  • Guy W. Neff
    • 1
    Email author
  • Grabriella Slapak-Green
    • 1
  • Thierry Berney
    • 1
  • Douglas Meyer
    • 1
  1. 1. Department of MedicineUniversity of MiamiMiamiUSA

Personalised recommendations