, Volume 65, Issue 3, pp 335–345 | Cite as

Stem cells for reprogramming: could hUMSCs be a better choice?

  • Paulina Duya
  • Yuhong Bian
  • Xiaoqian Chu
  • Yanjun Zhang
Review Paper


Human umbilical cord mesenchymal stem cells (hUMSC) are primitive multipotent cells capable of differentiating into cells of different lineages. They can be an alternative source of pluripotent cells since they are ethically and regulatory approved, are easily obtained and have low immunogenicity compared to embryonic stem cells which are dogged with numerous controversies. hUMSC can be a great source for cell and transplantation therapy.


Human umbilical cord mesenchymal stem cells Embryonic stem cells Pluripotency Reprogramming 



This work is supported by the National Natural Science Foundation of China (no. 81072741), National Basic Research Program of China (“973 Program”) (2011CB505300-02), Program for Changjiang Scholars and Innovative Research Team in University (no. IRT0973) and Tianjin Research Program Of Application Foundation And Advanced Technology (No.09jcybjc).


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Paulina Duya
    • 1
  • Yuhong Bian
    • 1
  • Xiaoqian Chu
    • 1
  • Yanjun Zhang
    • 1
  1. 1.Tianjin University of Traditional Chinese MedicineNankai districtChina

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