Secondary Metabolites from the Endophytic Fungus Fusarium equiseti and Their Antibacterial Activities
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Fusarium sp., a large genus of filamentous fungi, are endophytic fungi commonly derived from plant, which can produce many bioactive compounds such as terpenes, polyketides, nonribosomal peptides, and anthraquinones with antimicrobial, anti-inflammatory, and cytotoxic activities [1, 2, 3, 4].
As part of our ongoing investigation of bioactive compounds from the endophytic fungi from the Chinese medicinal plant Sophora tonkinensis [5, 6, 7], the fungus Fusarium equiseti attracted our attention. Eleven compounds, sterigmatocystin (1) , 5-methoxysterigmatocystin (2) , 5-methoxydihydrosterigmatocystin (3) , oxisterigmatocystin D (4) , averythrin (5) , anthraquinone aversin (6) , 6,8-di-O-methylaverufnin (7) , 6,8-di-O-methylnidurufin (8) , versicamide A (9) , emodin (10) , and ergosterol (11) , were isolated from the endophytic fungus F. equiseti, and their structures were established by comparison with those previously reported in the literature....
This work was supported by the National Natural Science Foundation of China (No. 21762007), the Guangxi Natural Science Foundation of China [Grant No. 2018GXNSFAA281169], the Project of State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University) (No. CMEMR2016-A06), and the Science Research and Technology Development Program of Guilin, China (No. 2016010301-2).