Advertisement

Chemistry of Natural Compounds

, Volume 55, Issue 6, pp 1141–1144 | Cite as

Secondary Metabolites from the Endophytic Fungus Fusarium equiseti and Their Antibacterial Activities

  • Xiao-Bo Liu
  • Na Zheng
  • Li-Qi Liang
  • Dong-Min Zhao
  • Yu-Yue Qin
  • Jun Li
  • Rui-Yun YangEmail author
Article
  • 19 Downloads

Fusarium sp., a large genus of filamentous fungi, are endophytic fungi commonly derived from plant, which can produce many bioactive compounds such as terpenes, polyketides, nonribosomal peptides, and anthraquinones with antimicrobial, anti-inflammatory, and cytotoxic activities [1, 2, 3, 4].

As part of our ongoing investigation of bioactive compounds from the endophytic fungi from the Chinese medicinal plant Sophora tonkinensis [5, 6, 7], the fungus Fusarium equiseti attracted our attention. Eleven compounds, sterigmatocystin (1) [8], 5-methoxysterigmatocystin (2) [9], 5-methoxydihydrosterigmatocystin (3) [10], oxisterigmatocystin D (4) [11], averythrin (5) [12], anthraquinone aversin (6) [9], 6,8-di-O-methylaverufnin (7) [13], 6,8-di-O-methylnidurufin (8) [14], versicamide A (9) [15], emodin (10) [16], and ergosterol (11) [17], were isolated from the endophytic fungus F. equiseti, and their structures were established by comparison with those previously reported in the literature....

Notes

Acknowledgment

This work was supported by the National Natural Science Foundation of China (No. 21762007), the Guangxi Natural Science Foundation of China [Grant No. 2018GXNSFAA281169], the Project of State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University) (No. CMEMR2016-A06), and the Science Research and Technology Development Program of Guilin, China (No. 2016010301-2).

References

  1. 1.
    F. Z. Wang, Y. C. Fang, M. Zhang, A. Q. Lin, T. J. Zhu, Q. Q. Gu, and W. M. Zhu, Steroids, 73, 19 (2008).CrossRefGoogle Scholar
  2. 2.
    C. L. Shao, C. Y. Wang, C. J. Zheng, Z. G. Shen, Y. C. Gu, and Y. C. Lin, Nat. Prod. Res., 24, 81 (2010).CrossRefGoogle Scholar
  3. 3.
    S. Kussari, S. Zuhlke, and M. Spiteller, J. Nat. Prod.,72, 2 (2009).CrossRefGoogle Scholar
  4. 4.
    P. B. Ratnaweera, E. D. De Silva, and R. J. Andersen, BCM. Complem. Altern. M, 15, 1 (2015).CrossRefGoogle Scholar
  5. 5.
    W. F. Xu, X. M. Hou, F. H. Yao, N. Zheng, J. Li, C. Y. Wang, R. Y. Yang, and C. L. Shao, Sci. Rep., 7, 1 (2017).CrossRefGoogle Scholar
  6. 6.
    Y. Liang, W. F. Xu, C. M. Liu, D. X. Zhou, X. B. Liu, Y. Y. Qin, F. Cao, J. Li, R. Y. Yang, and J. K. Qin, Nat. Prod. Res., 32, 1 (2018).CrossRefGoogle Scholar
  7. 7.
    N. Zheng, Q. Liu, D. L. He, Y. Liang, J. Li, and R. Y. Yang, Chem. Nat. Compd., 54, 447 (2018).CrossRefGoogle Scholar
  8. 8.
    F. Zhu, Y. C. Lin, S. N. Zhou, and L. L. P. Vrijmoed, Chin. J. Appl. Chem., 20, 272 (2003).Google Scholar
  9. 9.
    C. L. Shao, Z. G. She, Z. Y. Guo, H. P. X. L. Cai, S. N. Zhou, Y. C. Gu, and Y. C. Lin, Magn. Reson. Chem., 45, 434 (2007).CrossRefGoogle Scholar
  10. 10.
    F. H. Song, B. Ren, C. X. Chen, K. Yu, X. Liu, Y. Zhang, N. Yang, H. He, X. T. Liu, H. Q. Dai, and L. X. Zhang, Appl. Microbiol. Biotechnol., 98, 3753 (2014).CrossRefGoogle Scholar
  11. 11.
    H. Zhao, G. Q. Wang, X. P. Tong, G. D. Chen, Y. F. Huang, J. Y. Cui. M. Z. Kong, L. D. Guo, Y. Z. Zheng, X. S. Yao, and H. Gao, Fitoterapia, 98, 77 (2014).CrossRefGoogle Scholar
  12. 12.
    A. Stoessl and J. B. Stothers, Can. J. Chem.,63, 1258 (1985).CrossRefGoogle Scholar
  13. 13.
    D. G. I. Kingston, P. N. Chen, and J. R. Vercellotti, Phythochemistry, 15, 1037 (1976).CrossRefGoogle Scholar
  14. 14.
    H. Li, J. Wei, S. Y. Pan, J. M. Gao, and J. M. Tian, Nat. Prod. Res.,24, 2358 (2014).CrossRefGoogle Scholar
  15. 15.
    J. X. Peng, H. Q. Gao, J. Li, J. Ai, M. Y. Geng, G. J. Zhang, T. J. Zhu, Q. Q. Gu, and D. H. Li, J. Org. Chem., 79, 7895 (2014).CrossRefGoogle Scholar
  16. 16.
    S. F. Li, Y. T. Di, Y. H. Wang, C. J. Tan, X. Fang, Y. Zhang, Y. T. Zheng, L. Li, H. P. He, S. L. Li, and X. J. Hao, Helv. Chim. Acta., 93, 1795 (2010).CrossRefGoogle Scholar
  17. 17.
    C. Vladimir, O. Lubomir, G. D. Christopher, and B. Gerald, Phytochemistry, 8, 1669 (1997).Google Scholar
  18. 18.
    I. Wiegand, K. Hilpert, and R. E. Hancock, Nat. Protoc., 3, 163 (2008).CrossRefGoogle Scholar
  19. 19.
    J. Hoque, M. M. Konai, S. S. Sequeira, S. Samaddar, and J. Haldar, J. Med. Chem., 59, 10750 (2016).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Xiao-Bo Liu
    • 1
  • Na Zheng
    • 1
  • Li-Qi Liang
    • 1
  • Dong-Min Zhao
    • 1
  • Yu-Yue Qin
    • 1
  • Jun Li
    • 1
  • Rui-Yun Yang
    • 1
    Email author
  1. 1.State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, College of Chemistry and Pharmaceutical SciencesGuangxi Normal UniversityGuilinP. R. China

Personalised recommendations