Chemistry of Natural Compounds

, Volume 55, Issue 6, pp 1110–1114 | Cite as

Synthesis of Guanidine Derivatives of Methylcytisine

  • P. R. Petrova
  • A. V. Koval’skaya
  • A. N. Lobov
  • I. P. TsypyshevaEmail author

Guanidine derivatives of the quinolizidine alkaloid methylcytisine were synthesized by converting its 9-amino-derivative into the corresponding thiocarboxamide using phenylisothiocyanate and then into trisubstituted guanidines using HgCl2 in the presence of aromatic amines.


quinolizidine alkaloids methylcytisine guanidines 



The work was performed in the framework of a state task for UfIC, UFSC, RAS, on topics Nos. AAAA-A17-117011910025-6 and AAAA-A17-117011910027-0.


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • P. R. Petrova
    • 1
  • A. V. Koval’skaya
    • 1
  • A. N. Lobov
    • 1
  • I. P. Tsypysheva
    • 1
    Email author
  1. 1.Ufa Institute of Chemistry, Ufa Federal Research CenterRussian Academy of SciencesUfaRussia

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