Advertisement

Chemistry of Natural Compounds

, Volume 55, Issue 6, pp 1053–1055 | Cite as

A New Cerebroside from the Roots of Gynura procumbens

  • Ju-Wu Hu
  • Jing Wu
  • Xiong-Hui Li
  • Bin-Hua Huang
  • En Yuan
  • Lei WuEmail author
  • Guang-Qiang MaEmail author
Article
  • 9 Downloads

A new cerebroside (1), along with three known steroidal compounds, β-sitosterol (2), daucosterol (3), and stigmasterol (4), were isolated from the roots of Gynura procumbens (Lour.) Merr. The structure of 1 was determined to be 1-O-β-D-glucopyranosyl-(2R,6E,9R,12E)2-[(2′R)-2′-hydroxypentacosaneoyl-amino]-6,12-heptadecene-1,9-diol on the basis of chemical and spectroscopic evidence.

Keywords

Gynura procumbens Compositae cerebroside chemical constituents 

Notes

Acknowledgment

This work was kindly supported by the Foundation of Key Project of Research and Development Program of Jiangxi Province (Nos. 20171BBH80017 and 20171ACF60009), the Science and Technology Major Project Foundation of Jiangxi Academy of Sciences (2018-YZD1-05 and 2018-YZD2-18), and the Science Foundation for Young Doctors of Jiangxi Academy of Sciences (2016-YYB-07).

References

  1. 1.
    Yuandani, I. Jantan, and K. Husain, BMC. Complem. Altern. M., 17, 211 (2017).CrossRefGoogle Scholar
  2. 2.
    S. J. Bhore, N. Ravichantar, and C. Y. Loh, Bioinformation, 5, 191 (2010).CrossRefGoogle Scholar
  3. 3.
    C. S. Hew, B. Y. Khoo, and L. H. Gam, PLoS One, 8, e68524 (2017).CrossRefGoogle Scholar
  4. 4.
    N. Kaewseejan, V. Sutthikhum, and S. Siriamornpun, J. Funct. Foods., 12, 120 (2015).CrossRefGoogle Scholar
  5. 5.
    J. Kim, C. W. Lee, E. K. Kim, S. J. Lee, N. H. Park, H. S. Kim, and J. W. Kim, J. Ethnopharmacol., 137, 427 (2011).CrossRefGoogle Scholar
  6. 6.
    H. L. Tan, K. G. Chan, P. Pusparajah, L. H. Lee, and B. H. Goh, Front. Pharmacol., 7, 1 (2016).Google Scholar
  7. 7.
    A. Sadikun, I. Aminah, N. Ismail, and P. Ibrahim, Nat. Prod. Sci., 2, 19 (1996).Google Scholar
  8. 8.
    J. W. Hu, J. Wu, Y. Zhang, B. H. Huang, J. P. Fu, L. Wu, and G. Xu, Chem. Nat. Compd., 55, 583 (2019).CrossRefGoogle Scholar
  9. 9.
    S. R. Lee, K. Jung, H. J. Noh, Y. J. Park, H. L. Lee, K. R. Lee, K. S. Kang, and K. H. Kim, Bioorg. Med. Chem. Lett., 25, 5712 (2015).CrossRefGoogle Scholar
  10. 10.
    S. Sharma, S. K. Chattopadhyay, M. Singh, D. U. Bawankule, and S. Kumar, Phytochemistry, 100, 132 (2014).CrossRefGoogle Scholar
  11. 11.
    L. Chen, J. J. Wang, G. G. Zhang, H. T. Song, and L. P. Qin, Nat. Prod. Res., 23, 1330 (2009).CrossRefGoogle Scholar
  12. 12.
    J. Y. Zhang, S. B. Pu, S. H. Qian, and D. Liu, Chin. J. Nat. Med., 9, 105 (2011).Google Scholar
  13. 13.
    W. K. Zhang, J. K. Xu, X. Q. Zhang, X. S. Yao, and W. C. Ye, Chem. Phys. Lipids, 148, 77 (2007).CrossRefGoogle Scholar
  14. 14.
    W. W. Tao, N. Y. Yang, L. Liu, J. A. Duan, D. K. Wu, D. W. Qian, and Y. P. Tang, Fitoterapia, 81, 196 (2010).CrossRefGoogle Scholar
  15. 15.
    J. S. Yu, E. Moon, and K. H. Kim, Bioorg. Chem., 74, 122 (2017).CrossRefGoogle Scholar
  16. 16.
    X. S. Chen, Y. L. Wu, and D. H. Chen, Tetrahedron. Lett., 43, 3529 (2002).CrossRefGoogle Scholar
  17. 17.
    W. Y. Lin, M. H. Yen, C. M. Teng, I. L. Tsai, and I. S. Chen, J. Chin. Chem. Soc., 51, 1429 (2004).CrossRefGoogle Scholar
  18. 18.
    A. Q. Jia, X. Yang, W. X. Wang, and Y. H. Jia, Fitoterapia, 81, 540 (2010).CrossRefGoogle Scholar
  19. 19.
    L. Chen, J. J. Wang, H. T. Song, G. G. Zhang, and L. P. Qin, Chin. Chem. Lett., 20, 1091 (2009).CrossRefGoogle Scholar
  20. 20.
    L. Wu, W. Xiong, J. W. Hu, J. Wu, Z. J. Li, Y. Gao, C. L. Si, and Y. S. Bae, Chem. Nat. Compd., 55, 345 (2019).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Institute of Applied ChemistryJiangxi Academy of SciencesNanchangP. R. China
  2. 2.Jiangxi Hua Ziren Agricultural Development Co. Ltd.GanzhouP. R. China
  3. 3.Jiangxi University of Traditional Chinese MedicineNanchangP. R. China

Personalised recommendations