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Chemistry of Natural Compounds

, Volume 55, Issue 6, pp 1039–1042 | Cite as

Two New Xanthones from Comastoma pulmonarium and Their Anti-Tobacco Mosaic Virus Activity

  • Qiu-Fen Hu
  • Xiao-Long Wang
  • Wan-Li Zeng
  • Jin Wang
  • Yong Xu
  • Hai-Tao Huang
  • Jing Li
  • Xin Liu
  • Guang-Yu Yang
  • Xue-Mei Li
  • Cheng-Ming ZhangEmail author
  • Gang-Peng LiEmail author
Article
  • 23 Downloads

Two new xanthones (1 and 2), together with three known xanthones (3–5), were isolated from the whole plants of Comastoma pulmonarium. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 showed high anti-TMV activity with inhibition rates of 42.8% and 52.4%, respectively. These rates are higher than that of positive control.

Keywords

xanthones Comastoma pulmonarium anti-tobacco mosaic virus activity 

Notes

Acknowledgment

This research was supported by the National Natural Science Foundation of China (No. 21562047), the Research Foundation of China Tobacco Company (No. 110201502006), and the Research Foundation of China Tobacco Yunnan Industrial Co., Ltd. (No. 2017JC05).

References

  1. 1.
    H. G. Sun, Y. Niu, Y. S. Chen, B. Song, C. Q. Liu, D. L. Peng, J. G. Chen, and Y. Yang, J. Syst. Evol., 52, 378 (2014).CrossRefGoogle Scholar
  2. 2.
    T. N. He, S. W. Liu, and R. Wu, Flora of China, Vol. 62, Chinese Science Press, Beijing, 1988, p. 307.Google Scholar
  3. 3.
    B. X. Zhong, L. Tang, J. N. Jiao, L. Yang, and Y. Ma, J. Med. Pharm. Chin. Minorities, 6, 58 (2009).Google Scholar
  4. 4.
    X. C. Liu, Y. Zhao, Q. Y. Zeng, and P. C. Lin, Trad. Chin. Med., 9, 3760 (2016).Google Scholar
  5. 5.
    S. F. Fan, B. L. Hu, J. Y. Ding, and H. F. Sun, Acta Bot. Sin., 30, 307 (1988).Google Scholar
  6. 6.
    M. Zhou, K. Zhou, Y. L. Zhao, N. J. Xiang, T. D. Zhang, C. M. Zhang, Y. D. Wang, W. Dong, B. K. Ji, L. M. Li, J. Lou, G. P. Li, and Q. F. Hu, Heterocycles, 91, 604 (2015).CrossRefGoogle Scholar
  7. 7.
    M. Zhou, K. Zhou, Y. L. Zhao, N. J. Xiang, T. D. Zhang, Y. D. Wang, W. Dong, B. K. Ji, L. M. Li, J. Lou, G. P. Li, and Q. F. Hu, Phytochem. Lett., 11, 245 (2015).CrossRefGoogle Scholar
  8. 8.
    K. S. Masters and S. Brase, Chem. Rev., 112, 3717 (2012).CrossRefGoogle Scholar
  9. 9.
    M. V. Ignatushchenko, R. W. Winter, H. P. Bachinger, D. J. Hinrichs, and M. K. Riscoe, FEBS Lett., 409, 67 (1997).CrossRefGoogle Scholar
  10. 10.
    K. Likhitwitayawuid, T. Phadungcharoen, and J. Krungkrai, Planta Med., 64, 70 (1998).CrossRefGoogle Scholar
  11. 11.
    W. Wang, Y. Liao, X. Huang, C. Tang, and P. Cai, Nat. Prod. Res., 32, 1769 (2018).CrossRefGoogle Scholar
  12. 12.
    S. A. Suzy, H. Mieke, D. Warta, and S. Unang, Res. J. Chem. Environ, 22, 184 (2018).Google Scholar
  13. 13.
    Y. P. Wu, W. Zhao, Z. Y. Xia, G. H. Kong, X. P. Lu, Q. F. Hu, and X. M. Gao, Phytochem. Lett., 6, 629 (2013).CrossRefGoogle Scholar
  14. 14.
    W. Jiang, D. L. Zhu, M. F. Wang, Q. S. Yang, M. Y. Zuo, L. Zeng, and G. P. Li, Nat. Prod. Res., 30, 1810 (2015).CrossRefGoogle Scholar
  15. 15.
    H. Y. Yang, D. Y. Niu, L. Wang, S. J. Wang, C. M. Zhang, X. M. Gao, G. Du, and Q. F. Hu, J. Asian. Nat. Prod. Res., 17, 319 (2015).CrossRefGoogle Scholar
  16. 16.
    Q. F. Hu, D. Y. Niu, X. L. Li, Y. H. Qin, G. L. Zhao, Z. Y. Yang, X. M. Gao, and Z. Y. Chen, Heterocycles, 87, 1127 (2013).CrossRefGoogle Scholar
  17. 17.
    Y. H. Duan, Y. Dai, G. H. Wang, X. Zhang, H. F. Chen, J. B. Chen, X. S. Yao, and X. K. Zhang, J. Nat. Prod., 73, 1283 (2010).CrossRefGoogle Scholar
  18. 18.
    A. Rhodes, B. Boothroyd, M. P. M. Gonacle, and G. A. Somerfield, Biochem. J., 81, 28 (1961).PubMedPubMedCentralGoogle Scholar
  19. 19.
    R. R. Sun, F. P. Miao, J. Zhang, G. Wang, X. L. Yin, and N. Y. Jia, Magn. Reson. Chem., 51, 65 (2013).CrossRefGoogle Scholar
  20. 20.
    H. H. Xing, N. J. Xiang, L. X. Liu, G. R. Yang, Y. F. Shen, Y. Yang, L. Zhou, H. Y. Ma, M. Zhou, H. Y. Wu, G. P. Li, and Q. F. Hu, Chem. Nat. Compd., 53, 1052 (2017).CrossRefGoogle Scholar
  21. 21.
    Q. F. Hu, B. Zhou, J. M. Huang, X. M. Gao, L. D. Shu, G. Y. Yang, and C. T. Che, J. Nat. Prod., 76, 292 (2013).CrossRefGoogle Scholar
  22. 22.
    M. Zhou, K. Zhou, X. M. Gao, Z. Y. Jiang, J. J. Lv, Z. H. Liu, G. Y. Yang, M. M. Miao, C. T. Che, and Q. F. Hu, Org. Lett., 17, 2638 (2015).CrossRefGoogle Scholar

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Qiu-Fen Hu
    • 1
  • Xiao-Long Wang
    • 1
    • 2
  • Wan-Li Zeng
    • 2
  • Jin Wang
    • 2
  • Yong Xu
    • 2
  • Hai-Tao Huang
    • 2
  • Jing Li
    • 2
  • Xin Liu
    • 2
  • Guang-Yu Yang
    • 2
  • Xue-Mei Li
    • 2
  • Cheng-Ming Zhang
    • 2
    Email author
  • Gang-Peng Li
    • 1
    • 2
    Email author
  1. 1.Key Laboratory of Chemistry in Ethnic Medicinal ResourcesYunnan Minzu UniversityKunmingP. R. China
  2. 2.Key Laboratory of Tobacco Chemistry of Yunnan Province, China Tobacco Yunnan Industrial Co., Ltd.KunmingP. R. China

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