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Chemistry of Natural Compounds

, Volume 55, Issue 5, pp 797–801 | Cite as

Chemical Constituents of Microalgae Tetraselmis convolutae

  • Nguyen Thi Minh HangEmail author
  • Tran Huu Giap
  • Le Nguyen Thanh
  • Dang Diem Hong
  • Ngo Thi Hoai Thu
  • Chau Van Minh
Article
  • 46 Downloads

The first chemical investigation of the marine microalgae Tetraselmis convolutae is reported. Two phytyl esters, phytyl hexadeca-4,7-10,13-tetraenoate (1) and phytyl palmitate (2), and five other compounds, including phytol (3), hexadeca-4,7-10,13-tetraenoic acid (4), poriferasterol (5), palmitic acid (6), and glycerol (7), were isolated from the extracts of Tetraselmis convolutae. Compound 1 was isolated from nature for the first time, and it showed significant cytotoxic activity against KB, SK-LU-1, MCF7, and HepG2 cancer cell lines with IC50 values in the range of 65.23 ± 6.17–89.81 ± 5.83 μM/mL.

Keywords

Tetraselmis convolutae antimicrobial activity cytotoxic activity phytyl ester phytol poriferasterol 

Notes

Acknowledgment

The authors would like to express their thanks for the grants and financial support received from the Vietnam Academy of Science and Technology (Code: VAST.TD.DLB.07/16-18).

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Nguyen Thi Minh Hang
    • 1
    Email author
  • Tran Huu Giap
    • 1
  • Le Nguyen Thanh
    • 1
  • Dang Diem Hong
    • 2
  • Ngo Thi Hoai Thu
    • 2
  • Chau Van Minh
    • 1
  1. 1.Institute of Marine BiochemistryVietnam Academy of Science and Technology (VAST)HanoiVietnam
  2. 2.Institute of BiotechnologyVietnam Academy of Science and Technology (VAST)HanoiVietnam

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