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Chemistry of Natural Compounds

, Volume 55, Issue 4, pp 759–761 | Cite as

Serratanes from Whole Plant of Palhinhaea cernua

  • Lin-Fu Liang
  • Qiu-Han Chen
  • Jiang-Hao Xu
  • Ting Liu
  • Xiang-Nen Song
  • Hong-Yang Chen
  • Hong ChenEmail author
Article
  • 11 Downloads

The club moss Palhinhaea cernua (Lycopodium cernuum) of the family Lycopodiaceae is a perennial herb mainly distributed in Eastern and Southern China, the dried whole plant of which is historically used as a traditional Chinese medicine (TCM) for the treatment of rheumatism, whooping cough, contusions, scalds, hepatitis, and nephrolithiasis [1, 2]. Previously, an array of structurally interesting secondary metabolites, mainly serratane-type triterpenoids and Lycopodium alkaloids, were isolated from this plant [3, 4]. These isolated constituents have attracted a great deal of interest due of their wide range of biological activities, such as the inhibitory activities against cholinesterases and β-secretase 1, which were regarded as the key targets for the treatment of Alzheimer′s disease (AD) [3, 5]. As part of our research on structurally unique and biologically active metabolites from the Chinese medicinal plants [6], we investigated the title plant.

The dried and powdered whole plant...

Notes

Acknowledgment

This study was supported by the National Natural Science Foundation of China (41876194 and 41506187), the Hunan Provincial Natural Science Foundation of China (2015JJ3176), a Project Supported by Scientific Research Fund of Hunan Provincial Education Department (16C1674), and grants from Foshan University.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Lin-Fu Liang
    • 1
    • 2
  • Qiu-Han Chen
    • 1
  • Jiang-Hao Xu
    • 1
  • Ting Liu
    • 1
  • Xiang-Nen Song
    • 1
  • Hong-Yang Chen
    • 1
  • Hong Chen
    • 1
    • 2
    Email author
  1. 1.College of Materials Science and EngineeringCentral South University of Forestry and TechnologyChangshaP. R. China
  2. 2.School of Materials Science and Energy EngineeringFoshan UniversityFoshanP. R. China

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