Advertisement

Chemistry of Natural Compounds

, Volume 55, Issue 4, pp 648–650 | Cite as

Two New Naphthaldehyde Derivatives from Comastoma pulmonarium

  • Xiao-Long Wang
  • Ping Li
  • Hai-Ying Xiang
  • Wan-Li Zeng
  • Jing Li
  • Lin Ye
  • Xin Liu
  • Guang-Yu Yang
  • Qiu-Fen Hu
  • Xue-Mei Li
  • Gang-Peng Li
  • Cheng-Ming ZhangEmail author
Article
  • 9 Downloads

Two new naphthaldehyde derivatives, 2-(hydroxymethyl)-5-methoxy-7-(2-oxopropyl)naphthalene-1-carbaldehyde (1) and 2-(hydroxymethyl)-5-methyl-7-(2-oxopropyl)naphthalene-1-carbaldehyde (2), were isolated from the whole plants of Comastoma pulmonarium. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 showed high anti-TMV activity with inhibition rates of 34.6 and 30.2%, respectively.

Keywords

naphthaldehyde derivatives Comastoma pulmonarium anti-tobacco mosaic virus activity 

Notes

Acknowledgment

This research was supported by the National Natural Science Foundation of China (No. 21562047), the Research Foundation of China Tobacco Company (No. 110201502006), and the Research Foundation of China Tobacco Yunnan Industrial Co., Ltd. (Nos. 2015539200340277 and 2016JC03).

References

  1. 1.
    C. Zhang, R. E. Irwin, Y. Wang, Y. P. He, Y. P. Yang, and Y. W. Duan, New Phytol., 192, 249 (2011).CrossRefGoogle Scholar
  2. 2.
    B. X. Zhong, L. Tang, J. N. Jiao, L. Yang, and Y. Ma, J. Med. Pharm. Chin. Minorities., 6, 58 (2009).Google Scholar
  3. 3.
    S. F. Fan, B. L. Hu, J. Y. Ding, and H. F. Sun, Acta Bot. Sin., 30, 307 (1988).Google Scholar
  4. 4.
    M. Zhou, K. Zhou, Y. L. Zhao, N. J. Xiang, T. D. Zhang, C. M. Zhang, Y. D. Wang, W. Dong, B. K. Ji, L. M. Li, J. Lou, G. P. Li, and Q. F. Hu, Heterocycles, 91, 604 (2015).CrossRefGoogle Scholar
  5. 5.
    M. Zhou, K. Zhou, Y. L. Zhao, N. J. Xiang, T. D. Zhang, Y. D. Wang, W. Dong, B. K. Ji, L. M. Li, J. Lou, G. P. Li, and Q. F. Hu, Phytochem. Lett., 11, 245 (2015).CrossRefGoogle Scholar
  6. 6.
    M. Rosenblatt, N. Engl. J. Med., 376, 52 (2017).CrossRefGoogle Scholar
  7. 7.
    R. A. Dixon, Nature, 411 (6839), 843 (2001).CrossRefGoogle Scholar
  8. 8.
    S. R. M. Ibrahim and G. A. Mohamed, Phytochem. Rev., 15, 279 (2016).CrossRefGoogle Scholar
  9. 9.
    M. Zhou, G. Du, H. Y. Yang, C. F. Xia, J. X. Yang, Y. Q. Ye, X. M. Gao, X. N. Li, and Q. F. Hu, Planta Med., 81, 235 (2015).CrossRefGoogle Scholar
  10. 10.
    Q. F. Hu, B. Zhou, J. M. Huang, X. M. Gao, L. D. Shu, G. Y. Yang, and C. T. Che, J. Nat. Prod., 76, 292 (2013).CrossRefGoogle Scholar
  11. 11.
    M. Zhou, K. Zhou, X. M. Gao, Z. Y. Jiang, J. J. Lv, Z. H. Liu, G. Y. Yang, M. M. Miao, C. T. Che, and Q. F. Hu, Org. Lett., 17, 2638 (2015).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Xiao-Long Wang
    • 1
    • 2
  • Ping Li
    • 1
    • 2
  • Hai-Ying Xiang
    • 1
  • Wan-Li Zeng
    • 1
  • Jing Li
    • 1
  • Lin Ye
    • 1
  • Xin Liu
    • 1
  • Guang-Yu Yang
    • 1
  • Qiu-Fen Hu
    • 1
  • Xue-Mei Li
    • 1
  • Gang-Peng Li
    • 2
  • Cheng-Ming Zhang
    • 1
    Email author
  1. 1.China Tobacco Yunnan Industrial Co., LtdKunmingP. R. China
  2. 2.Key Laboratory of Chemistry in Ethnic Medicinal ResourcesYunnan Minzu UniversityKunmingP. R. China

Personalised recommendations