Chemistry of Natural Compounds

, Volume 55, Issue 4, pp 610–613 | Cite as

A New Neolignan Glucoside from the Stems of “Baekma” Cultivar, Chrysanthemum morifolium

  • Hyoung-Geun Kim
  • Hyun-Ji Oh
  • Jung-Hwan Ko
  • Sun-Woo Joo
  • Yeong-Geun Lee
  • Yun-Su Baek
  • Dae Young Lee
  • Nam-In BaekEmail author

A new neolignan glucoside has been isolated from Chrysanthemum morifolium ‘Baekma’ cultivar through repeated silica gel and octadecyl silica gel (ODS) column chromatographies. On the basis of spectroscopic data including NMR, MS, and IR, the chemical structure of the new neolignan glucoside was determined to be (7S,8S)-7-O-[1′-(4′,5′-dihydroxy-3′-methoxyphenyl)propanol]guaiacylglycerol 4-O-β-D-glucopyranoside (1), named baekmaoside A.


Baekma baekmaoside A Chrysanthemum morifolium neolignan glucoside 



This work was supported by the Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry, and Fisheries (317071-03-1-SB020).


  1. 1.
    F. Wang, F. J. Zhang, F. D. Chen, W. M. Fang, and N. J. Teng, Scientific World J., 2014, 9 (2014).Google Scholar
  2. 2.
    Ministry of Agriculture, Food and Rural Affairs, 2016 Flower Cultivation Status [Korean translation], Saejong, Korea, 2017, p. 13.Google Scholar
  3. 3.
    Horticulture Industry Newspaper, in: Research Archievement in Division of Floriculture Research [in Korean], Horticulture Industry Newspaper, 2016, online article []
  4. 4.
    L. X. Chen, D. J. Hu, S. C. Lam, L. Ge, D. Wu, J. Zhao, Z. R. Long, W. J. Yang, B. Fan, and S. P. Li, J. Chromatogr. A, 1428, 134 (2016).CrossRefGoogle Scholar
  5. 5.
    L. Zhang, H. Fu, J. Tian, W. Wang, X. Zhai, R. Li, and W. Li, CN Pat. No. 2011-10184646, Shuomingsh, Gongkai, Faming Zhuanli Shenqing, 2011.Google Scholar
  6. 6.
    L. Qu, S. Bu, J. Li, L. Han, T. Wang, and Y. Zhang, Shenyang Yaoke Daxue, 33, 525 (2016).Google Scholar
  7. 7.
    J. S. Nam, S. Y. Park, H. L. Jang, and Y. H. Rhee, Appl. Biol. Chem., 60, 535 (2017).CrossRefGoogle Scholar
  8. 8.
    C. H. Park, M. J. Ahn, G. S. Hwang, S. E. An, and W. K. Whang, Appl. Biol. Chem., 59, 485 (2016).CrossRefGoogle Scholar
  9. 9.
    S. L. Spassov, Tetrahedron, 25, 3631 (1969).CrossRefGoogle Scholar
  10. 10.
    C. Shi, M. J. Xu, M. Bayer, Z. W. Deng, M. H. G. Kubbutat, W. Waejen, P. Proksch, and W. H. Lin, Phytochemistry, 71, 435 (2010).CrossRefGoogle Scholar
  11. 11.
    N. Nguyen Thi, H. S. Song, E. J. Oh, Y. G. Lee, J. H. Ko, J. E. Kwon, S. C. Kang, D. Y. Lee, I. H. Jung, and N. I. Baek, Appl. Biol. Chem., 60, 527 (2017).CrossRefGoogle Scholar
  12. 12.
    J. Lee, J. P. Rodriguez, K. H. Lee, J. Y. Park, K. S. Kang, D. H. Hahm, C. K. Huh, S. C. Lee, and S. Lee, Appl. Biol. Chem., 60, 487 (2017).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Hyoung-Geun Kim
    • 1
  • Hyun-Ji Oh
    • 1
  • Jung-Hwan Ko
    • 1
  • Sun-Woo Joo
    • 1
  • Yeong-Geun Lee
    • 1
  • Yun-Su Baek
    • 2
  • Dae Young Lee
    • 3
  • Nam-In Baek
    • 1
    Email author
  1. 1.Graduate School of Biotechnology and Department of Oriental Medicinal BiotechnologyKyung Hee UniversityYonginRepublic of Korea
  2. 2.Sauces Industrialization DepartmentAgency for Korea National Food Cluster (AnFC), IPETWanjuRepublic of Korea
  3. 3.Department of Herbal Crop ResearchNational Institute of Horticultural and Herbal Science, RDAEumseongRepublic of Korea

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