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Phenolic Compounds from the Aerial Part of Geranium transversale and Their Antimicrobial Activity

  • D. R. SiddikovEmail author
  • Kh. M. Bobakulov
  • S. Z. Nishanbaev
  • S. A. Sasmakov
  • N. D. Abdullaev
  • Sh. S. Azimova
Article
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Species of the genus Geranium L. (Geraniaceae, including ~300 species) are promising sources of polyphenols [1, 2, 3]. Uzbekistan is home to 13 geranium species [4, 5] that are used in folk medicine as astringent, disinfectant, hemostatic, and anti-inflammatory agents and to treat malignant tumors, diarrhea, dysentery, colic, insomnia, epilepsy, fever, rheumatism, and other diseases [6].

Phenolic compounds from geraniums (flavonoids including proanthocyanidins and others) possess broad spectra of biological activity such as antiviral, antimicrobial, hypoglycemic, antidiarrheal, antioxidant, diuretic, antiprotozoal, and anti-inflammatory activity [7, 8, 9, 10, 11, 12, 13, 14].

The plant G. transversale Vved. ex Pavlov is a perennial herbaceous plant distributed over Uzbekistan [4, 5] and was chosen for the studies. Volatile compounds [15] and the contents of tanning agents in the aerial part (7.2%), stems (3.2%), leaves (7.4%), and flowers (10.9%) of G. transversale [16, 17] were...

Notes

Acknowledgment

The work was financially supported by the Basic Research Programs, AS, RUz (Grants TA-FA-F7-008, VA-FA-F-6-010, and FA-F6-T198).

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • D. R. Siddikov
    • 1
    Email author
  • Kh. M. Bobakulov
    • 1
  • S. Z. Nishanbaev
    • 1
  • S. A. Sasmakov
    • 1
  • N. D. Abdullaev
    • 1
  • Sh. S. Azimova
    • 1
  1. 1.S. Yu. Yunusov Institute of the Chemistry of Plant SubstancesAcademy of Sciences of the Republic of UzbekistanTashkentUzbekistan

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