Additional Chemical Constituents of an Endophytic Fungus Xylaria papulis
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Endophytic fungi living in a plant’s internal tissues or organs without causing any immediate overt negative effects or apparent symptoms [1, 2, 3] in the host plant have been viewed as excellent sources of natural products with unique structures and interesting biological characteristics. The research on endophytes showed that they are rich sources of diverse secondary metabolites [2, 3, 4, 5, 6]. In previous research done by our group for secondary metabolites from endophytic fungi, a series of new compounds was isolated with biological activities. As a part of our ongoing program, we report the isolation and structural elucidation of the five additional constituents from the BuOH extract of the cultures of an endophytic fungus Xylaria papulis, which was isolated from the stem of Taiwanese Lepidagathis stenophylla C. B. Clarke ex Hayata (Acanthaceae) growing in the Hengchun Peninsula of southern Taiwan. The structures of known compounds 1-5 were established by comparison of their 1H...
This investigation was supported by a grant from the Ministry of Economic Affairs of the Republic of China. The authors also thank Senior Technician Mrs. Chyi-Jia Wang of the Center for Resources, Research, and Development (CRRD) of Kaohsiung Medical University for measuring the 2D NMR data.
- 8.V. S. P. Chaturvedula and R. Huang, J. Pharmacogn. Phytochem., 2, 113 (2013).Google Scholar