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Additional Chemical Constituents of an Endophytic Fungus Xylaria papulis

  • Ming-Jen ChengEmail author
  • Ming-Der Wu
  • Yung-Shun Su
  • Hing-Yuen Chan
  • Sung-Yuan Hsieh
  • Yen-Lin Chen
  • Jih-Jung Chen
  • Yu-Ta Chou
  • Yen-Chen Hsiao
  • Hsiu-Shan Wu
Article
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Endophytic fungi living in a plant’s internal tissues or organs without causing any immediate overt negative effects or apparent symptoms [1, 2, 3] in the host plant have been viewed as excellent sources of natural products with unique structures and interesting biological characteristics. The research on endophytes showed that they are rich sources of diverse secondary metabolites [2, 3, 4, 5, 6]. In previous research done by our group for secondary metabolites from endophytic fungi, a series of new compounds was isolated with biological activities. As a part of our ongoing program, we report the isolation and structural elucidation of the five additional constituents from the BuOH extract of the cultures of an endophytic fungus Xylaria papulis, which was isolated from the stem of Taiwanese Lepidagathis stenophylla C. B. Clarke ex Hayata (Acanthaceae) growing in the Hengchun Peninsula of southern Taiwan. The structures of known compounds 1-5 were established by comparison of their 1H...

Notes

Acknowledgment

This investigation was supported by a grant from the Ministry of Economic Affairs of the Republic of China. The authors also thank Senior Technician Mrs. Chyi-Jia Wang of the Center for Resources, Research, and Development (CRRD) of Kaohsiung Medical University for measuring the 2D NMR data.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Ming-Jen Cheng
    • 1
    Email author
  • Ming-Der Wu
    • 1
  • Yung-Shun Su
    • 2
    • 3
  • Hing-Yuen Chan
    • 1
  • Sung-Yuan Hsieh
    • 1
  • Yen-Lin Chen
    • 1
  • Jih-Jung Chen
    • 4
    • 5
  • Yu-Ta Chou
    • 6
  • Yen-Chen Hsiao
    • 7
  • Hsiu-Shan Wu
    • 7
  1. 1.Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI)HsinchuTaiwan
  2. 2.Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical UniversityKaohsiungTaiwan
  3. 3.Su Yung-Shun Dermatology ClinicKaohsiungTaiwan
  4. 4.Faculty of Pharmacy, School of Pharmaceutical SciencesNational Yang-Ming UniversityTaipeiTaiwan
  5. 5.Department of Medical ResearchChina Medical University HospitalTaichungTaiwan
  6. 6.Department of Obstetrics & Gynecology, E-Da HospitalI-Shou UniversityKaohsiungTaiwan
  7. 7.Department of Nursing, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University HospitalKaohsiung Medical UniversityKaohsiungTaiwan

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