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Chemical Constituents of the Leaves of Elaeagnus grandifolia

  • Y. S. Tsai
  • C. T. Chen
  • H. C. Yeh
  • H. T. LiEmail author
  • C. Y. ChenEmail author
Article

There are about 90 species of Elaeagnus around the world. The majority are native to the temperate and subtropical regions in Asia, of which nine species can be found in Taiwan [1]. Many species of Elaeagnus are considered as folk medicinal plants, e.g., E. umbellate [2], E. pungens [3], E. angustifolia [4], and E. multiflora [5]. Triterpenoids, steroids and flavonoids have been isolated from several species of Elaeagnus, e.g., E. ungens [6], E. umbellate [6], E. bockii [7], E. orientalis [8], and E. pungens [9, 10]. In the course of screening for biologically and chemically novel agents from Formosan eleagnaceous plants, E. grandifolia Hayata was chosen for further phytochemical investigation. This is also being studied and published for the first time.

These observations provide useful information for potential chemopreventive drug design. The MeOH extract of its leaves was subjected to solvent partitioning and chromatographic separation to afford 11 pure substances. The chemical...

Notes

Acknowledgment

This investigation was supported by a grant from the Yuan′s General Hospital awarded to C. L. Lin.

References

  1. 1.
    T. S. Huang, Elaeagnaceae, In Flora of Taiwan, 2nd ed.; Editorial Committee of the Flora of Taiwan, Vol. 3, Taipei, Taiwan, 1998, p. 753.Google Scholar
  2. 2.
    S. D. Ahmad, M. S. Sabir, M. Juma, and H. S. Asad, Acta Bot. Croat., 64, 121 (2005).Google Scholar
  3. 3.
    G. Yuebin, J. Liu, and D. Su, J. Ethnopharmacol., 126, 538 (2009).CrossRefGoogle Scholar
  4. 4.
    A. Ahmadiani, J. Hosseiny, S. Semnanian, M. Javan, F. Saeedi, M. Kamalinejad, and S. Saremi, J. Ethnopharmacol., 72, 287 (2000).CrossRefGoogle Scholar
  5. 5.
    Y. S. Lee, Z. Q. Chang, B. C. Oh, S, C. Park, S. R. Shin, and N. W. Kim, J. Med. Food, 10, 126 (2007).CrossRefGoogle Scholar
  6. 6.
    Y. C. Fu and X. J. Wang, Qilu Pharm. Affairs, 26, 232 (2007).Google Scholar
  7. 7.
    F. M. Lou, J. Yang, Z. C. Bai, and B. F. Wu, Zhongguo Zhong Yao Za Zhi, 31, 988 (2006).Google Scholar
  8. 8.
    M. Ayaz, M. Riaz, A. Malik, E. Ahmad, and I. Fatima, Nat. Prod. Res., 23, 409 (2009).CrossRefGoogle Scholar
  9. 9.
    Y. B. Ge, M. S. Li, Z. N. Mei, and G. Z. Yang, J. Asian Nat. Prod. Res., 15, 1073 (2013).CrossRefGoogle Scholar
  10. 10.
    Y. B. Wu, Y. Gu, and M. A. Ouyang, J. Asian Nat. Prod. Res., 12, 278 (2010).CrossRefGoogle Scholar
  11. 11.
    T. H. Babu, K. Manjulatha, G. S. Kumar, A. Hymavathi, A. K. Tiwari, M. Purohit, J. M. Rao, and K. S. Babu, Bioorg. Med. Chem. Lett., 20, 117 (2010).CrossRefGoogle Scholar
  12. 12.
    W. W. Jiang, J. P. Kou, Z. Zhang, and B. Y. Yu, Thromb. Res., 124, 714 (2009).CrossRefGoogle Scholar
  13. 13.
    B. M. Fraga, M. G. Hernandez, C. Fernandez, and J. M. Santana, Phytochemistry, 70, 1038 (2009).CrossRefGoogle Scholar
  14. 14.
    W. X. Li, C. B. Cui, B. Cai, H. Y. Wang, and X. S. Yao, J. Asian Nat. Prod. Res., 7, 615 (2005).CrossRefGoogle Scholar
  15. 15.
    W. L. Lo, Y. C. Wu, T. J. Hsieh, S. H. Kuo, H. C. Lin, and C. Y. Chen, Chin. Pharm. J., 56, 69 (2004).Google Scholar
  16. 16.
    C. Y. Chen, L. Y. Huang, L. J. Chen, W. L. Lo, S. Y. Kuo, Y. D. Wang, S. H. Kuo, and T. J. Hsieh, Chem. Nat. Compd., 44, 137 (2008).CrossRefGoogle Scholar
  17. 17.
    H. K. Wang and K. H. Lee, Bot. Bull. Acad. Sin., 38, 225 (1997).Google Scholar
  18. 18.
    J. R. Luo, H. E. Jiang, Y. X. Zhao, and J. Zhao, Chem. Nat. Compd., 44, 6 (2008).Google Scholar
  19. 19.
    W. S. Sheen, I. L. Tsai, C. M. Teng, and I. S. Chen, Phytochemistry, 36, 213 (1994).CrossRefGoogle Scholar
  20. 20.
    T. J. Hsieh, S. F. Hsieh, and C. Y. Chen, Chem. Nat. Compd., 46, 99 (2010).CrossRefGoogle Scholar

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of PathologyFooyin University HospitalKaohsiungTaiwan
  2. 2.Department of Medical Sciences Industry, College of Health SciencesChang Jung Christian UniversityTainanTaiwan
  3. 3.Department of Medical Laboratory Science and BiotechnologyFooyin UniversityKaohsiungTaiwan
  4. 4.School of Medical and Health SciencesFooyin UniversityKaohsiungTaiwan

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