Chemical Constituents of the Leaves of Elaeagnus grandifolia

  • Y. S. Tsai
  • C. T. Chen
  • H. C. Yeh
  • H. T. LiEmail author
  • C. Y. ChenEmail author

There are about 90 species of Elaeagnus around the world. The majority are native to the temperate and subtropical regions in Asia, of which nine species can be found in Taiwan [1]. Many species of Elaeagnus are considered as folk medicinal plants, e.g., E. umbellate [2], E. pungens [3], E. angustifolia [4], and E. multiflora [5]. Triterpenoids, steroids and flavonoids have been isolated from several species of Elaeagnus, e.g., E. ungens [6], E. umbellate [6], E. bockii [7], E. orientalis [8], and E. pungens [9, 10]. In the course of screening for biologically and chemically novel agents from Formosan eleagnaceous plants, E. grandifolia Hayata was chosen for further phytochemical investigation. This is also being studied and published for the first time.

These observations provide useful information for potential chemopreventive drug design. The MeOH extract of its leaves was subjected to solvent partitioning and chromatographic separation to afford 11 pure substances. The chemical...



This investigation was supported by a grant from the Yuan′s General Hospital awarded to C. L. Lin.


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Authors and Affiliations

  1. 1.Department of PathologyFooyin University HospitalKaohsiungTaiwan
  2. 2.Department of Medical Sciences Industry, College of Health SciencesChang Jung Christian UniversityTainanTaiwan
  3. 3.Department of Medical Laboratory Science and BiotechnologyFooyin UniversityKaohsiungTaiwan
  4. 4.School of Medical and Health SciencesFooyin UniversityKaohsiungTaiwan

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