Chemical Constituents of Polygonatum sibiricum
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Polygonatum sibiricum is distributed widely in most areas of the northern temperate zone [1, 2, 3]. Its dried root has been used as a folk medicine for thousands of years, and it shows anti-inflammatory, immunoregulatory, and anti-diabetic activities [4, 5, 6]. It is well known that the therapeutic effects of a plant depend on its chemical constituents. Isolation and characterization of a plant′s constituents can enable identification of potentially active compounds. Much research has been devoted to studying the active compounds in P. sibiricum to clarify the mechanisms of the therapeutic effects of this plant. In recent years, many types of compound, e.g., polysaccharides , alkaloids , steroidal saponins , and triterpenoid saponins  have been isolated from P. sibiricum. However, there have been few reports of other important classes of compounds such as homoisoflavonoids, coumarins, and anthraquinones. These classes of compounds are widely found in many plant genera and...
This work was financially supported by the National Natural Science Foundation of China (No. 81303191) and the Beichen Science Technology Development Foundation (No. 2016-SHGY-19). We thank Helen McPherson, PhD, from Liwen Bianji, Edanz Editing China (www.liwenbianji.cn/ac), for editing the English text of a draft of this manuscript.