Chemical Constituents of Dolomiaea berardioidea

  • Ying-ying Huang
  • Yang-guo Xie
  • Sheng-lan Zhu
  • Shi-kai YanEmail author
  • Hui-zi JinEmail author

The genus Dolomiaea comprises approximately 12 species widely distributed in the southwest of China, and a few are in Myanmar [1]. Previous research has shown that the genus Dolomiaea is a rich source of sesquiterpenes, triterpenes, steroids, phenylpropanoids, and flavonoids.

Dolomiaea berardioidea, commonly known as “Hou Ye Chuan Mu Xiang” in traditional Chinese medicine, is mainly scattered in Lijiang, Yunnan Province, China [2]. In order to study the bioactive compounds of the whole plants of D. berardioidea, we isolated and identified nine compounds, including five aromatic compounds, three phenylpropanoids, and one monoterpene: trichomanin (1) [3], 1,2-benzenedicarboxylic acid diisobutyl ester (2) [4], hydroxytyrosol (3) [5], 3-methoxy-4-hydroxyphenethanol (4) [6], 4-hydroxy-3-methoxyphenetyl acetate (5) [7], umbelliferone (6) [8], (+)-prinsepiol (7) [9], (+)-syringaresinol (8) [10], and vomifoliol (9) [11]. All compounds were obtained from this plant for the first time.

The whole...


  1. 1.
    Flora of China, Science Press, 78 (1), 141 (1978).Google Scholar
  2. 2.
    Flora of China, Science Press, 78 (1), 147 (1978).Google Scholar
  3. 3.
    X. N. Wang, W. T. Yu, and H. X. Lou, Chem. Biodiv., 2, 140 (2005).Google Scholar
  4. 4.
    W. Zhang, H. X. Lou, G. Y. Li, and H. M. Wu, J. Asian Nat. Prod. Res., 5, 189 (2003).CrossRefGoogle Scholar
  5. 5.
    R. W. Owen, W. Mier, A. Giacosa, W. E. Hull, B. Spiegelhalder, and H. Bartsch, Clin. Chem., 46 (7), 976 (2000).Google Scholar
  6. 6.
    R. N. Tang, X. B. Qu, S. H. Guan, P. P. Xu, Y. Y. Shi, and D. A. Guo, Chin. J. Nat. Med., 10 (1), 32 (2012).CrossRefGoogle Scholar
  7. 7.
    S. Grasso, L. Siracusa, C. Spatafora, M. Renis, and C. Tringali, Bioorg. Chem., 35, 137 (2007).CrossRefGoogle Scholar
  8. 8.
    R. Singh, B. Singh, S. Singh, N. Kumar, S. Kumar, and S. Arora, Food Chem., 120, 825 (2010).CrossRefGoogle Scholar
  9. 9.
    S. B. Kilidhar, M. R. Parthasarathy, and P. Sharma, Phytochemistry, 796, 21 (1982).CrossRefGoogle Scholar
  10. 10.
    Y. Y. Song, Y. Liu, Y. M. Yan, X. F. Lu, and Y. X. Cheng, Molecules, 23 (3), 580 (2018).CrossRefGoogle Scholar
  11. 11.
    Q. Y. Zhang, Y. Y. Zhao, T. M. Cheng, Y. Cui, and X. Liu, J. Asian Nat. Prod. Res., 2 (2), 81 (2000).CrossRefGoogle Scholar

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.School of PharmacyShanghai Jiao Tong UniversityShanghaiP. R. China

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